Indox 100 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxycycline hydrochloride |
| Company | Indo bangla pharmaceutical |
Title
Indox Broad-Spectrum Antibiotic
Categories
- Pharmaceuticals
- Medicine
- Health & Wellness
Description
Indox is a highly active broad-spectrum antibiotic of tetracycline group. It is effective against a wide range of Gram-positive and Gram-negative bacteria, spirochete, mycoplasma, rickettsia and mycobacteria. Indox is used as an alternate to penicillin in the treatment of gonorrhoea and syphilis. Indox has its main mechanism of action on protein synthesis.
Indications
- Respiratory tract infections
- Gastrointestinal tract infections
- Chlamydial infections
- Sexually transmitted diseases
- Other infections
Dosage
- Usual dose: 200 mg on first day, then 100 mg daily for 7-10 days.
- Severe infections (including refractory urinary tract infections): 200 mg daily for 10 days.
- Acne: 100 mg daily.
- Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days (14-21 days in pelvic inflammatory disease).
Administration
Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing.
Mode of Action
Doxycycline Hydrochloride is a semisynthetic tetracycline antibiotic with broad spectrum activity. It is primarily a bacteriostatic antibiotic.
Pharmacology
Doxycycline is active against most strains of Haemophilus influenzae and is particularly useful for infections with H. ducreyi, Actinomyces, Brucella and Vibrio cholerae.
Interaction
Absorption of tetracyclines is impaired by antacid containing aluminium, calcium or magnesium, and iron containing preparation. Absorption of tetracyclines is also impaired by bismuth salicylate. Barbiturates, carbamazepine and phenytoin decrease half-life of doxycycline.
Contraindications
Doxycycline is contraindicated to the patients who have shown hypersensitivity to any of the tetracyclines. It is also contraindicated to the children under 8 years of age, pregnant women, and lactating mothers.
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Skin rashes
- Hemolytic anaemia
- Eosinophilia
Pregnancy & Lactation
Doxycycline should be avoided in pregnant women, because of the risk of both staining and effect on bone growth in the foetus. Doxycyclines enter breast milk, and mothers taking these drugs should not breastfeed their child.
Precautions & Warnings
The use of drugs of the tetracycline class during tooth development may cause permanent discoloration of teeth.
Therapeutic Class
Tetracycline group of drugs
Storage Conditions
Keep all medicines out of reach of children. Store in a cool and dry place, protected from light.