Velacin 100 mg (Capsule)
Unit Price: ৳ 1.02 (100's pack: ৳ 102.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxycycline hydrochloride |
| Company | Doctors chemical works ltd |
Title
- Velacin
Categories
- Antibiotics
- Tetracycline Group
- Broad-Spectrum Antibiotics
Description
- Highly active broad-spectrum antibiotic of tetracycline group
- Effective against a wide range of Gram-positive and Gram-negative bacteria, spirochete, mycoplasma, rickettsia, and mycobacteria
- Used as an alternate to penicillin in the treatment of gonorrhoea and syphilis
- Main mechanism of action is on protein synthesis
Indications
- Respiratory tract infections
- Gastrointestinal tract infections
- Chlamydial infections
- Sexually transmitted diseases
- Other infections
Pharmacology
- Semisynthetic tetracycline antibiotic with broad-spectrum activity
- Primarily a bacteriostatic antibiotic
- More active against Staphylococcus aureus and Nocardia
- Active against certain Gram-negative strains
- Active against Haemophilus influenzae, H. ducreyi, Actinomyces, Brucella, Vibrio cholerae, Nocardia, Chlamydia, Mycoplasma, and a wide range of Rickettsiae
- Active against spirochetes such as Borellia recurrentis, Treponema pallidum, and Treponema pertenue
- Active against Plasmodium falciparum
Dosage
- Usual dose: 200 mg on first day, then 100 mg daily for 7-10 days
- Severe infections (including refractory urinary tract infections): 200 mg daily for 10 days
- Acne: 100 mg daily
- Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days
Administration
- Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing
Interaction
- Absorption of tetracyclines is impaired by antacids containing aluminium, calcium or magnesium, and iron-containing preparations
- Absorption of tetracyclines is also impaired by bismuth salicylate
- Barbiturates, carbamazepine, and phenytoin decrease half-life of doxycycline
- Concurrent use of tetracyclines may render oral contraceptives less effective
- Patients on anticoagulant therapy may require downward adjustment of their anticoagulant dosages
- It is advisable to avoid giving tetracyclines in conjunction with penicillin
Contraindications
- Hypersensitivity to any of the tetracyclines
- Children under 8 years of age
- Pregnant women
- Lactating mothers
Side effects
- Nausea
- Vomiting
- Diarrhoea
- Skin rashes
- Hemolytic anaemia
- Eosinophilia
Pregnancy lactation
- Avoid in pregnant women due to the risk of staining and effect on bone growth in the foetus
- Doxycyclines enter breast milk, and mothers taking these drugs should not breastfeed their child
Precautions warnings
- The use of drugs of the tetracycline class during tooth development may cause permanent discoloration of teeth in children
Therapeutic class
- Tetracycline group of drugs
Storage conditions
- Keep all medicines out of reach of children
- Store in a cool and dry place, protected from light