Pristin OL 5 mg+50 mg (Tablet)

Unit Price: ৳ 5.02 (30's pack: ৳ 150.48)

Medicine Details

Title

  • Amlodipine and Atenolol 5/25 mg Tablet

Categories

  • Antihypertensive Medication
  • Cardiovascular Medication

Description

  • A fixed-dose combination of Amlodipine and Atenolol used to treat essential hypertension, angina pectoris, post myocardial infarction, and refractory angina pectoris

Dosage

Amlodipine and Atenolol 5/25 mg tablet once daily. Dosage may be increased to 5/25 mg two tablets daily if advised by physicians.

Indications

  • Essential hypertension
  • Angina pectoris & hypertension coexistence
  • Post myocardial infarction
  • Refractory angina pectoris

Pharmacology

  • Amlodipine - Dihydropyridine calcium antagonist
  • Amlodipine - Peripheral vasodilator
  • Atenolol - Cardioselective beta-blocker

Interaction

  • Disopyramide - Reduced clearance by Atenolol
  • Ampicillin - Potential reduction in Atenolol levels
  • Oral antidiabetics and insulin - Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion

Contraindications

  • Hypersensitivity to either component
  • Sinus bradycardia
  • Second and higher degrees of heart block
  • Cardiogenic shock
  • Hypotension
  • Congestive heart failure
  • Poor left ventricular function

Side Effects

  • Fatigue
  • Headache
  • Edema
  • Nausea
  • Drowsiness
  • Anxiety
  • Depression

Pregnancy & Lactation

Use during pregnancy only if benefit outweighs potential risk. Not recommended for nursing mothers.

Precautions & Warnings

  • Bronchospasm
  • Renal impairment
  • Hepatic impairment
  • Drug withdrawal

Overdose Effects

  • Hypotension
  • Congestive cardiac failure

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

Store below 30°C, away from light & moisture, out of reach of children

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