Sidoplus 5 mg+25 mg (Tablet)

Unit Price: ৳ 6.00 (4 x 10: ৳ 240.00)

Strip Price: ৳ 60.00

Medicine Details

Category	Details
Generic	Amlodipine besilate atenolol
Company	Eskayef pharmaceuticals ltd
Also available as	Sidoplus 5 mg tablet

Indications

Essential hypertension
Angina pectoris
Post myocardial infarction
Refractory angina pectoris

Pharmacology

Dihydropyridine calcium antagonist
Peripheral vasodilator
Beta-blocker
Reduction in blood pressure
Reduction in cardiac demand
Reduction in peripheral vascular resistance

Dosage & Administration

Recommended dosage of Amlodipine and Atenolol 5/25 mg tablet once daily
Dosage may be increased to 5/25 mg two tablets daily
Dosage should be individualized

Interaction

Disopyramide - reduces clearance by 20%
Ampicillin - may reduce Atenolol levels
Oral antidiabetics and insulin - may decrease tissue sensitivity to insulin and inhibit insulin secretion

Contraindications

Hypersensitivity to either component
Sinus bradycardia
Second and higher degrees of heart block
Cardiogenic shock
Hypotension
Congestive heart failure
Poor left ventricular function

Side Effects

Fatigue
Headache
Edema
Nausea
Drowsiness
Anxiety
Depression

Pregnancy & Lactation

Use during pregnancy only if expected benefit outweighs potential fetal risk
Should not be used by nursing mothers
Breastfeeding should be stopped if use is considered necessary

Precautions & Warnings

Bronchospasm - caution in patients with airway obstruction
Renal impairment - can be used in patients with renal impairment
Hepatic impairment - caution in patients with severe liver damage
Drug withdrawal - discontinuation should be gradual and under observation

Overdose Effects

Hypotension
Congestive cardiac failure
Unabsorbed drugs may be removed by gastric lavage or administration of activated charcoal

Therapeutic Class

Combined antihypertensive preparations

Storage Conditions

Keep below 30°C temperature
Away from light & moisture
Keep out of the reach of children

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