Sidoplus 5 mg+25 mg (Tablet)
Unit Price: ৳ 6.00 (4 x 10: ৳ 240.00)
Strip Price: ৳ 60.00
Medicine Details
Category | Details |
---|---|
Generic | Amlodipine besilate atenolol |
Company | Eskayef pharmaceuticals ltd |
Also available as |
Indications
- Essential hypertension
- Angina pectoris
- Post myocardial infarction
- Refractory angina pectoris
Pharmacology
- Dihydropyridine calcium antagonist
- Peripheral vasodilator
- Beta-blocker
- Reduction in blood pressure
- Reduction in cardiac demand
- Reduction in peripheral vascular resistance
Dosage & Administration
- Recommended dosage of Amlodipine and Atenolol 5/25 mg tablet once daily
- Dosage may be increased to 5/25 mg two tablets daily
- Dosage should be individualized
Interaction
- Disopyramide - reduces clearance by 20%
- Ampicillin - may reduce Atenolol levels
- Oral antidiabetics and insulin - may decrease tissue sensitivity to insulin and inhibit insulin secretion
Contraindications
- Hypersensitivity to either component
- Sinus bradycardia
- Second and higher degrees of heart block
- Cardiogenic shock
- Hypotension
- Congestive heart failure
- Poor left ventricular function
Side Effects
- Fatigue
- Headache
- Edema
- Nausea
- Drowsiness
- Anxiety
- Depression
Pregnancy & Lactation
- Use during pregnancy only if expected benefit outweighs potential fetal risk
- Should not be used by nursing mothers
- Breastfeeding should be stopped if use is considered necessary
Precautions & Warnings
- Bronchospasm - caution in patients with airway obstruction
- Renal impairment - can be used in patients with renal impairment
- Hepatic impairment - caution in patients with severe liver damage
- Drug withdrawal - discontinuation should be gradual and under observation
Overdose Effects
- Hypotension
- Congestive cardiac failure
- Unabsorbed drugs may be removed by gastric lavage or administration of activated charcoal
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children