A-Mycin 250 mg (Tablet)
Unit Price: ৳ 5.15 (10 x 10: ৳ 515.00)
Strip Price: ৳ 51.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Erythromycin oral |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Upper respiratory tract infections
- Lower respiratory tract infections
- Ear infections
- Eye infections
- Skin and Soft tissue infections
- Gastrointestinal tract infections
- Prophylaxis
- Osteomyelitis
- Diptheria
- Scarlet fever
- Whooping cough
Description
- Belongs to the macrolides group of antibiotics
- Exerts bacteriostatic or bactericidal action
- Specific interference with ribosomal protein synthesis
- Mainly used for the treatment of infections caused by penicillinase producing staphylococci
- Susceptible micro-organisms: Gram (+)ve : Cocci and bacilli, Gram (-)ve : Neisseria catarhalis, N.meningitis, N.gonorrhoea, Haemophilus influenzae, Brodetella, H. pertussis, Mycoplasma pneumoniae, Legionella pneumophila, Bacteroides fragilis, B.oralis, B.melaninogenicus, Fusobacterium, Chlamydia trachomatis, Treponema pallidum
Pharmacology
- Inhibits microsomal protein synthesis in susceptible organisms
- Binding to the 50S subunit or 70S ribosome
- Active against Grampositive bacteria, some Gram-negative bacteria, mycoplasmas and chlamydia
- Absorption: Destroyed by acid, administered as stable ester
- Blood concentration: Peak serum concentrations
- Distribution: Widely distributed throughout body tissue and fluids, with some retention in the liver and spleen
- Excretion: Excreted in the urine and bile
Dosage & Administration
- Dosage range for adults and children over 8 years
- Dosage for elderly patients
- Dosage for children aged 2 to 8 years
- Dosage for infants and children upto 2 years
Interaction
- Potential interaction with theophylline
Contraindications
- Known hypersensitivity to Erythromycin
Side Effects
- Occasional abdominal discomfort after oral administration
- Rare allergic reactions, mild anaphylaxis
- Nausea and vomiting
Pregnancy & Lactation
- Caution for pregnant patients and lactating mothers
Precautions & Warnings
- Careful administration in patients with impaired hepatic function
Overdose Effects
- Discontinuation in case of overdosage
Therapeutic Class
- Anti-diarrhoeal Antimicrobial drugs
- Macrolides
Reconstitution
- Direction for reconstitution of suspension
- Shake well before each use
- Storage guidelines for reconstituted suspension
Storage Conditions
- Temperature and environmental storage conditions