A-Mycin 250 mg (Tablet)

Unit Price: ৳ 5.15 (10 x 10: ৳ 515.00)
Strip Price: ৳ 51.50

Medicine Details

Category Details
Generic Erythromycin oral
Company Aristopharma ltd
Also available as
A mycin 500 mg tablet A mycin 125 mg suspension A mycin 250 mg suspension A mycin 200 mg pediatric drop

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Ear infections
  • Eye infections
  • Skin and Soft tissue infections
  • Gastrointestinal tract infections
  • Prophylaxis
  • Osteomyelitis
  • Diptheria
  • Scarlet fever
  • Whooping cough

Description

  • Belongs to the macrolides group of antibiotics
  • Exerts bacteriostatic or bactericidal action
  • Specific interference with ribosomal protein synthesis
  • Mainly used for the treatment of infections caused by penicillinase producing staphylococci
  • Susceptible micro-organisms: Gram (+)ve : Cocci and bacilli, Gram (-)ve : Neisseria catarhalis, N.meningitis, N.gonorrhoea, Haemophilus influenzae, Brodetella, H. pertussis, Mycoplasma pneumoniae, Legionella pneumophila, Bacteroides fragilis, B.oralis, B.melaninogenicus, Fusobacterium, Chlamydia trachomatis, Treponema pallidum

Pharmacology

  • Inhibits microsomal protein synthesis in susceptible organisms
  • Binding to the 50S subunit or 70S ribosome
  • Active against Grampositive bacteria, some Gram-negative bacteria, mycoplasmas and chlamydia
  • Absorption: Destroyed by acid, administered as stable ester
  • Blood concentration: Peak serum concentrations
  • Distribution: Widely distributed throughout body tissue and fluids, with some retention in the liver and spleen
  • Excretion: Excreted in the urine and bile

Dosage & Administration

  • Dosage range for adults and children over 8 years
  • Dosage for elderly patients
  • Dosage for children aged 2 to 8 years
  • Dosage for infants and children upto 2 years

Interaction

  • Potential interaction with theophylline

Contraindications

  • Known hypersensitivity to Erythromycin

Side Effects

  • Occasional abdominal discomfort after oral administration
  • Rare allergic reactions, mild anaphylaxis
  • Nausea and vomiting

Pregnancy & Lactation

  • Caution for pregnant patients and lactating mothers

Precautions & Warnings

  • Careful administration in patients with impaired hepatic function

Overdose Effects

  • Discontinuation in case of overdosage

Therapeutic Class

  • Anti-diarrhoeal Antimicrobial drugs
  • Macrolides

Reconstitution

  • Direction for reconstitution of suspension
  • Shake well before each use
  • Storage guidelines for reconstituted suspension

Storage Conditions

  • Temperature and environmental storage conditions

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