A-Mycin 500 mg (Tablet)

Unit Price: ৳ 9.00 (5 x 10: ৳ 450.00)
Strip Price: ৳ 90.00

Medicine Details

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of ear infections
  • Treatment of eye infections
  • Treatment of skin and soft tissue infections
  • Treatment of gastrointestinal tract infections
  • Prophylaxis for pre and post-operative, trauma, burns, rheumatic fever
  • Treatment of osteomyelitis
  • Treatment of diptheria
  • Treatment of scarlet fever
  • Treatment of whooping cough

Description

  • Belongs to the macrolides group of antibiotics
  • Exerts a bacteriostatic or bactericidal action
  • Interferes with ribosomal protein synthesis within the bacterial cell
  • Used for penicillinase producing staphylococci
  • Particularly susceptible to Gram positive and negative micro-organisms

Pharmacology

  • Inhibits microsomal protein synthesis
  • Binds to the 50S subunit or 70S ribosome
  • Active against Gram positive and some Gram negative bacteria
  • Active against mycoplasmas and chlamydia
  • Destroyed by acid and administered in the form of stable ester
  • Widely distributed throughout body tissue and fluids
  • Enters the cerebrospinal fluid when the meninges are inflamed
  • Crosses the placenta and is excreted in the milk
  • 5 to 15 % excreted in the urine
  • Large amounts excreted in the bile

Dosage & Administration

  • Dosage for adults and children over 8 years
  • Dosage for elderly
  • Dosage for children aged 2 to 8 years
  • Dosage for infants and children up to 2 years

Interaction

  • Potential interaction with theophylline

Contraindications

  • Known hypersensitivity to Erythromycin

Side Effects

  • Rare allergic reactions
  • Mild anaphylaxis
  • Abdominal discomfort
  • Nausea and vomiting

Pregnancy & Lactation

  • No evidence of teratogenicity or toxicity in humans
  • Caution for pregnant patients and lactating mothers

Precautions & Warnings

  • Given with care in patients with impaired hepatic function

Overdose Effects

  • Prompt discontinuation in case of overdosage
  • Prompt elimination of unabsorbed drug
  • A-Mycin is not removed by peritoneal dialysis or haemodialysis

Therapeutic Class

  • Anti-diarrhoeal Antimicrobial drugs
  • Macrolides

Reconstitution

  • Directions for reconstitution of suspension

Storage Conditions

  • Keep below 25°C temperature
  • Away from light and moisture
  • Keep out of the reach of children

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