Erocin 250 mg (Tablet)

Unit Price: ৳ 5.18 (50's pack: ৳ 259.00)

Medicine Details

Category Details
Generic Erythromycin oral
Company Acme laboratories ltd
Also available as
Erocin 500 mg tablet Erocin 125 mg suspension

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of ear infections
  • Treatment of eye infections
  • Treatment of skin and soft tissue infections
  • Treatment of gastrointestinal tract infections
  • Prophylaxis for various infections
  • Treatment of osteomyelitis
  • Treatment of diptheria
  • Treatment of scarlet fever
  • Treatment of whooping cough

Description

  • Belongs to macrolides group of antibiotics
  • Exerts bacteriostatic or bactericidal action
  • Effective against penicillinase producing staphylococci
  • Susceptible to various micro-organisms
  • Inhibits microsomal protein synthesis
  • Active against Gram-positive and some Gram-negative bacteria

Pharmacology

  • Inhibits microsomal protein synthesis in susceptible organisms
  • Specific binding to 50S subunit or 70S ribosome
  • Active against Gram-positive bacteria and some Gram-negative bacteria
  • Rate of absorption diminished by presence of food
  • Widely distributed throughout body tissue and fluids
  • Enters cerebrospinal fluid and crosses placenta
  • Excreted in urine and bile

Dosage & Administration

  • Dosage for adults and children over 8 years
  • No special dosage recommendation for elderly
  • Dosage for children aged 2 to 8 years
  • Dosage for infants and children up to 2 years

Interaction

  • May increase serum theophylline levels
  • Potential theophylline toxicity
  • Requires reduction in theophylline dose

Contraindications

  • Known hypersensitivity to Erythromycin

Side Effects

  • Rare allergic reactions
  • Mild anaphylaxis may occur
  • Occasional abdominal discomfort, nausea, vomiting

Pregnancy & Lactation

  • No evidence of teratogenicity or toxicity in humans
  • Caution advised for pregnant patients
  • Erythromycin crosses placental barrier and is excreted in breast milk

Precautions & Warnings

  • Careful use in patients with impaired hepatic function

Overdose Effects

  • Discontinue Erocin in case of overdosage
  • Prompt elimination of unabsorbed drug
  • Not removed by peritoneal dialysis or haemodialysis

Therapeutic Class

  • Anti-diarrhoeal antimicrobial drug
  • Macrolides

Reconstitution

  • Direction for reconstitution of suspension
  • Shake bottle to loosen powder
  • Add boiled and cooled water to the dry powder
  • Shake well after each addition
  • Keep reconstituted suspension in cool and dry place
  • Discard unused portion after 7 days

Storage Conditions

  • Keep below 25°C temperature
  • Away from light and moisture
  • Keep out of the reach of children

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