Tenocab 5 mg+50 mg (Tablet)

Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Amlodipine besilate atenolol
Company Aci limited
Also available as
Tenocab 5 mg tablet

Indications

  • Essential hypertension
  • Angina pectoris with hypertension
  • Post myocardial infarction
  • Refractory angina pectoris

Pharmacology

  • Fixed-dose combination of Amlodipine and Atenolol
  • Amlodipine inhibits calcium influx into vascular smooth muscle and cardiac muscle
  • Amlodipine acts as a peripheral vasodilator
  • Atenolol is a cardioselective beta-blocker
  • Atenolol reduces blood pressure
  • Atenolol reduces myocardial oxygen demand

Dosage & Administration

  • Recommended dosage: Amlodipine and Atenolol 5/25 mg tablet once daily
  • Dosage may be increased to 5/25 mg two tablets daily or as advised by physicians
  • Dosage should be individualized

Interaction

  • Interaction with Disopyramide: Atenolol reduces clearance and may produce additive negative inotropic effects
  • Interaction with Ampicillin: May reduce Atenolol levels
  • Interaction with Oral antidiabetics and insulin: Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion

Contraindications

  • Hypersensitivity to either component
  • Sinus bradycardia
  • Second and higher degrees of heart block
  • Cardiogenic shock
  • Hypotension
  • Congestive heart failure
  • Poor left ventricular function

Side Effects

  • Well-tolerated combination
  • Side-effects include fatigue, headache, edema, nausea, drowsiness, anxiety, depression

Pregnancy & Lactation

  • Use during pregnancy only if expected benefit outweighs potential fetal risk
  • Not recommended for nursing mothers

Precautions & Warnings

  • Use with caution in patients with airway obstruction
  • Can be used in patients with renal impairment
  • Caution in severe liver damage patients
  • Warning against sudden drug withdrawal

Overdose Effects

  • Hypotension
  • Congestive cardiac failure
  • Unabsorbed drugs may be removed by gastric lavage or administration of activated charcoal
  • Symptomatic treatment recommended

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Keep below 30°C temperature, away from light & moisture, keep out of reach of children

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