Eromycin 200 mg/5 ml (Pediatric Drops)
60 ml drop: ৳ 75.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Erythromycin oral |
| Company | Square pharmaceuticals plc |
| Also available as |
Title
- Eromycin 500mg Tablet
Categories
- Antibiotics
- Macrolides
- Antimicrobial Drugs
Description
- Effective in treating a wide variety of clinical infections
Indications
- Upper respiratory tract infections
- Lower respiratory tract infections
- Ear infections
- Eye infections
- Skin and soft tissue infections
- Gastrointestinal tract infections
- Prophylaxis
- Other infections
Pharmacology
- Belongs to the macrolides group of antibiotics
- Exerts a bacteriostatic or bactericidal action
- Inhibits microsomal protein synthesis in susceptible organisms
Absorption
- Erythromycin base is destroyed by acid
- Administered in the form of stable ester
- Diminished absorption rates in the presence of food
Blood concentration
- Peak serum concentrations of 0.9 to 1.4 mg/ml
- Attained in 1 to 4 hours
- Half-life of 1.2 to 4 hours
Distribution
- Widely distributed throughout body tissue and fluids
- Some retention in the liver and spleen
- Protein binding of erythromycin base is 73%
Excretion
- 5 to 15% of the dose excreted in the urine
- Large amounts of the unchanged active substance excreted in the bile
Dosage administration
- Adult and Children over 8 years: 250-500 mg every six hours for mild to moderate infections
- Elderly: No special dosage recommendation
- Children aged 2 to 8 years: 250 mg every six hours
- Infants and Children upto 2 years: 500 mg in divided doses
Interaction
- May increase serum theophylline levels and potential theophylline toxicity
- Dose of theophylline should be reduced in such cases
Contraindications
- Known hypersensitivity to Erythromycin
Side effects
- Rare allergic reactions
- Mild abdominal discomfort
- Occasional nausea and vomiting
Pregnancy lactation
- Caution should be exercised when prescribing to pregnant patients and lactating mothers
- Erythromycin crosses the placental barrier and is excreted in breast milk
Precautions warnings
- Given with care in patients with impaired hepatic function
- Excreted principally in the bile
Overdose effects
- Should be discontinued in case of overdosage
- Prompt elimination of unabsorbed drug
- Not removed by peritoneal or haemodialysis
Therapeutic class
- Anti-diarrhoeal Antimicrobial drugs
- Macrolides
Reconstitution
- Shake the bottle to loosen powder
- Add 60ml or 100ml of boiled and cooled water to the dry powder
- Suspension should be stored in a cool and dry place, preferably in refrigerator
- Unused portion should be discarded after 7 days
Storage conditions
- Keep below 25°C temperature
- Away from light & moisture
- Keep out of the reach of children