Erosa 250 mg (Tablet)

Unit Price: ৳ 4.52 (10 x 10: ৳ 452.00)

Strip Price: ৳ 45.20

Medicine Details

Category	Details
Generic	Erythromycin oral
Company	Biopharma limited
Also available as	Erosa 500 mg tablet Erosa 125 mg suspension

Upper respiratory tract infections: Tonsillitis, Peritonsillar abscess, Pharyngitis, Laryngitis, Sinusitis
Lower respiratory tract infections: Tracheitis, Acute and chronic bronchitis
Ear infections: Otitis media, Otitis externa, Mastoiditis
Eye infections: Blepharitis, Established trachoma
Skin and soft tissue infections: Boils and carbuncles, Impetigo, Abscesses, Pustular acne, Paronychia, Cellulitis, Erysipelas
Gastrointestinal tract infections: Cholecystitis, Staphylococcal enterocolitis
Prophylaxis: Pre and post-operative, Trauma, Burns, Rheumatic fever
Other infections: Osteomyelitis, Diphtheria, Scarlet fever, Whooping cough

Belongs to the macrolides group of antibiotics
Exerts a bacteriostatic or bactericidal action based on specific interference with ribosomal protein synthesis within the bacterial cell
Used for the treatment of infections caused by penicillinase producing staphylococci
Particularly susceptible to Gram (+)ve : Cocci and bacilli, Gram (-)ve : Neisseria catarhalis, N.meningitis, N.gonorrhoea, Haemophilus influenzae, Brodetella, H. pertussis, Mycoplasma pneumoniae, Legionella pneumophila, Bacteroides fragilis, B.oralis, B.melaninogenicus, Fusobacterium, Chlamydia trachomatis, Treponema pallidum

Inhibits microsomal protein synthesis in susceptible organisms by inhibiting the translocation process
Active against many Gram-positive bacteria, some Gram-negative bacteria, mycoplasmas, and chlamydia
Destroyed by acid and administered in the form of stable ester
Widely distributed throughout body tissue and fluids with some retention in the liver and spleen
Enters the cerebrospinal fluid when the meninges are inflamed, crosses the placenta, and excreted in the milk

Adult and Children over 8 years: 250-500 mg every six hours for mild to moderate infections, may be increased up to 4 gm. or more daily in severe cases
Elderly: No special dosage recommendation, may be administered three times daily or twice daily by giving one-third or half of the total daily requirement 8 hourly or 12 hourly respectively
Children aged 2 to 8 years: 250 mg every six hours or 30-50 mg/kg body weight per day divided into four equal dosage
Infants and Children up to 2 years: 500 mg in divided doses or 30-50 mg/kg body weight in divided doses

Use in patients receiving high dosage of theophylline may be associated with an increase of serum theophylline levels and potential theophylline toxicity
In such cases, the dose of theophylline should be reduced

Allergic reactions are rare and mild, although anaphylaxis has occurred
Occasional abdominal discomfort after oral administration, sometimes with nausea and vomiting

No evidence in human of teratogenicity or toxicity in clinical and laboratory studies
Caution should be exercised when prescribing this drug to pregnant patients and lactating mothers since erythromycin crosses the placental barrier and is excreted in breast milk

Should be given with care in patients with impaired hepatic function, as it is excreted principally in the bile

Erythromycin should be discontinued
Overdosage should be handled with the prompt elimination of unabsorbed drug and all other appropriate measures should be instituted
Not removed by peritoneal dialysis or hemodialysis

Direction for reconstitution of suspension: Add 60 ml or 100 ml of boiled and cooled water to the dry powder of the bottle, shake well after each addition until all the powder is in suspension
The reconstituted suspension should be stored in a cool and dry place, preferably in the refrigerator and the unused portion should be discarded after 7 days

Keep below 25°C temperature, away from light and moisture, keep out of the reach of children