E-Rox 500 mg (Tablet)

Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Erythromycin oral
Company Desh pharmaceuticals ltd
Also available as
E rox 125 mg suspension

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Ear infections
  • Eye infections
  • Skin and Soft tissue infections
  • Gastrointestinal tract infections
  • Prophylaxis
  • Osteomyelitis
  • Diptheria
  • Scarlet fever
  • Whooping cough

Description

  • Belongs to the macrolides group of antibiotics
  • Exerts a bacteriostatic or bactericidal action
  • Used for the treatment of infections caused by penicillinase producing staphylococci
  • Particularly susceptible to Gram (+)ve and Gram (-)ve micro-organisms
  • Active against Mycoplasma pneumoniae, Legionella pneumophila, Bacteroides fragilis

Pharmacology

  • Inhibits microsomal protein synthesis in susceptible organisms
  • Absorption rate impacted by the presence of food
  • Widely distributed throughout body tissue and fluids
  • Enters the cerebrospinal fluid when the meninges are inflamed
  • Excreted in the urine and bile

Dosage & Administration

  • Adult dosage: 250-500 mg every six hours for mild to moderate infections
  • Elderly dosage: No special recommendation
  • Children aged 2 to 8 years: 250 mg every six hours or 30-50 mg/kg body weight per day
  • Infants and Children upto 2 years: 500 mg in divided doses or 30-50 mg/kg body weight in divided doses

Interaction

  • Use may increase serum theophylline levels and potential theophylline toxicity
  • Requires reduced theophylline dosage in such cases

Contraindications

  • Known hypersensitivity to Erythromycin

Side Effects

  • Rare and mild allergic reactions
  • Occasional abdominal discomfort after oral administration
  • May cause nausea and vomiting

Pregnancy & Lactation

  • No evidence of human teratogenicity or toxicity in clinical and laboratory studies
  • Caution advised for pregnant patients and lactating mothers due to crossing the placental barrier and excretion in breast milk

Precautions & Warnings

  • Administer with care in patients with impaired hepatic function

Overdose Effects

  • Prompt discontinuation of E-Rox in case of overdosage
  • Handling with the prompt elimination of unabsorbed drug
  • Not removed by peritoneal dialysis or haemodialysis

Therapeutic Class

  • Anti-diarrhoeal Antimicrobial drugs
  • Macrolides

Reconstitution

  • Shake the bottle to loosen powder
  • Add boiled and cooled water to the dry powder
  • Shake well after each addition until all the powder is in suspension
  • Shake the suspension well before each use
  • Store reconstituted suspension in a cool and dry place
  • Unused portion should be discarded after 7 days

Storage Conditions

  • Keep below 25°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

Related Brands