Erythin 125 mg/5 ml (Powder for Suspension)
Medicine Details
Category | Details |
---|---|
Generic | Erythromycin oral |
Company | Aci limited |
Indications
- Upper respiratory tract infections
- Lower respiratory tract infections
- Ear infections
- Eye infections
- Skin and Soft tissue infections
- Gastrointestinal tract infections
- Prophylaxis
- Other infections
Description
Belongs to macrolides group of antibiotics
Micro-organisms Susceptible
- Gram (+)ve : Cocci and bacilli
- Gram (-)ve : Neisseria catarhalis, N.meningitis, N.gonorrhoea, Haemophilus influenzae, Brodetella, H. pertussis
- Other micro-organisms : Mycoplasma pneumoniae, Legionella pneumophila, Bacteroides fragilis, B.oralis, B.melaninogenicus, Fusobacterium, Chlamydia trachomatis, Treponema pallidum
Mode of Action
Inhibits microsomal protein synthesis in susceptible organisms
Absorption
Base is destroyed by acid, administered in the form of stable ester
Blood Concentration
Peak serum concentrations reached in 1 to 4 hours
Distribution
Widely distributed throughout body tissue and fluids
Excretion
5 to 15% excreted in urine, large amounts in bile
Dosage & Administration
Varies by age group and severity of infection
Interaction
May increase serum theophylline levels
Contraindications
Known hypersensitivity to Erythromycin
Side Effects
- Allergic reactions
- Abdominal discomfort
- Nausea
- Vomiting
Pregnancy & Lactation
Crosses placental barrier, excreted in breast milk
Precautions & Warnings
Given with care in patients with impaired hepatic function
Overdose Effects
Discontinue in case of overdosage
Therapeutic Class
Anti-diarrhoeal Antimicrobial drugs, Macrolides
Reconstitution
Direction for reconstitution of suspension provided
Storage Conditions
Keep below 25°C, away from light & moisture, out of the reach of children
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