Eryzen 500 mg (Tablet)

Unit Price: ৳ 8.66 (5 x 4: ৳ 173.20)

Strip Price: ৳ 34.64

Medicine Details

Category	Details
Generic	Erythromycin oral
Company	Zenith pharmaceuticals ltd
Also available as	Eryzen 250 mg tablet Eryzen 125 mg suspension

Upper respiratory tract infections: Tonsillitis, Peritonsillar abscess, Pharyngitis, Laryngitis, Sinusitis
Lower respiratory tract infections: Tracheitis, Acute and chronic bronchitis
Ear infections: Otitis media, Otitis externa, Mastoiditis
Eye infections: Blepharitis, Established trachoma
Skin and soft tissue infections: Boils and carbuncles, Impetigo, Abscesses, Pustular acne, Paronychia, Cellulitis, Erysipelas
Gastrointestinal tract infections: Cholecystitis, Staphylococcal enterocolitis
Prophylaxis: Pre and post-operative, Trauma, Burns, Rheumatic fever
Other infections: Osteomyelitis, Diphtheria, Scarlet fever, Whooping cough

Belongs to the macrolides group of antibiotics
Exerts bacteriostatic or bactericidal action based on specific interference with ribosomal protein synthesis
Mainly used for the treatment of infections caused by penicillinase producing staphylococci
Particularly susceptible to Gram (+)ve : Cocci and bacilli, Gram (-)ve : Neisseria catarhalis, N. meningitis, N. gonorrhoea, Haemophilus influenzae, Brodetella, H. pertussis, Mycoplasma pneumoniae, Legionella pneumophila, Bacteroides fragilis, B. oralis, B. melaninogenicus, Fusobacterium, Chlamydia trachomatis, Treponema pallidum

Inhibits microsomal protein synthesis in susceptible organisms
Binds specifically to the 50S subunit or 70S ribosome in susceptible organisms
Active against many Gram-positive and some Gram-negative bacteria, mycoplasmas, and chlamydia
Destroyed by acid so administered in the form of stable ester
Widely distributed throughout body tissue and fluids with some retention in the liver and spleen
Enters the cerebrospinal fluid when the meninges are inflamed
Crosses the placenta and is excreted in the milk

Adult and Children over 8 years: 250-500 mg every six hours for mild to moderate infections, may be increased up to 4 gm or more daily in severe cases
Elderly: No special dosage recommendation
Children aged 2 to 8 years: 250 mg every six hours or 30-50 mg/kg body weight per day divided into four equal dosages
Infants and Children up to 2 years: 500 mg in divided doses or 30-50 mg/kg body weight in divided doses

Use in patients receiving high dosage of theophylline may be associated with an increase of serum theophylline levels and potential theophylline toxicity

Allergic reactions are rare and mild, although anaphylaxis has occurred
Occasional abdominal discomfort after oral administration, sometimes with nausea and vomiting

No evidence in human of teratogenicity or toxicity
Caution should be exercised when prescribing this drug to pregnant patients and lactating mothers

Should be given with care in patients with impaired hepatic function, as it is excreted principally in the bile

Shake the bottle to loosen powder
Add prescribed amount of boiled and cooled water to the dry powder
Shake the suspension well before each use
Store in a cool and dry place, preferably in refrigerator and discard unused portion after 7 days