Tenopin 5 mg+50 mg (Tablet)

Unit Price: ৳ 4.51 (3 x 10: ৳ 135.30)
Strip Price: ৳ 45.10

Medicine Details

Indications

  • Essential hypertension
  • Angina pectoris & hypertension
  • Post myocardial infarction
  • Refractory angina pectoris

Pharmacology

  • Fixed-dose combination of Amlodipine and Atenolol
  • Amlodipine inhibits transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle
  • Amlodipine acts as a peripheral vasodilator
  • Amlodipine reduces peripheral vascular resistance and blood pressure
  • Atenolol is a cardioselective beta-blocker
  • Atenolol lowers cardiac output and plasma renin activity

Dosage & Administration

Recommended dosage of Amlodipine and Atenolol is 5/25 mg tablet once daily

Interactions

  • Atenolol reduces the clearance of disopyramide
  • Ampicillin may reduce Atenolol levels
  • Beta-blockers may decrease tissue sensitivity to insulin

Contraindications

  • Hypersensitivity to either component
  • Sinus bradycardia
  • Cardiogenic shock
  • Hypotension
  • Congestive heart failure

Side Effects

  • Fatigue
  • Headache
  • Edema
  • Nausea
  • Drowsiness
  • Anxiety
  • Depression

Pregnancy & Lactation

Use during pregnancy should outweigh potential fetal risk; not recommended during lactation

Precautions & Warnings

  • Caution in patients with airway obstruction
  • Caution in patients with renal impairment
  • Caution in patients with severe liver damage
  • Caution against sudden drug withdrawal

Overdose Effects

Hypotension and congestive cardiac failure may occur in cases of overdosage

Therapeutic Class

Combined antihypertensive preparations

Storage Conditions

Keep below 30°C, away from light & moisture, and out of the reach of children

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