Ilocin 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 60.00

Medicine Details

Category Details
Generic Erythromycin oral
Company Doctors chemical works ltd
Also available as
Ilocin 500 mg tablet

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Ear infections
  • Eye infections
  • Skin and soft tissue infections
  • Gastrointestinal tract infections
  • Prophylaxis
  • Osteomyelitis
  • Diptheria
  • Scarlet fever
  • Cholecystitis
  • Staphylococcal enterocolitis

Description

Belongs to the macrolides group of antibiotics

Micro-organisms Susceptible

  • Gram positive: Cocci and bacilli
  • Gram negative: Neisseria catarhalis, N.meningitis, N.gonorrhoea, Haemophilus influenzae, Brodetella, H. pertussis
  • Other micro-organisms: Mycoplasma pneumoniae, Legionella pneumophila, Bacteroides fragilis, B.oralis, B.melaninogenicus, Fusobacterium, Chlamydia trachomatis, Treponema pallidum

Pharmacology

  • Mode of Action: Interference with ribosomal protein synthesis
  • Absorption: Destroyed by acid, stable ester form
  • Blood Concentration: Peak serum concentrations 0.9 to 1.4 or 0.4 to 1.8 mg/ml
  • Distribution: Widely distributed throughout body tissue and fluids
  • Excretion: 5 to 15% excreted in urine, excreted in the bile

Dosage & Administration

  • Adult and Children over 8 years: 250-500 mg every six hours for mild to moderate infections (may be increased for severe cases)
  • Elderly: No special dosage recommendation
  • Children aged 2 to 8 years: 250 mg every six hours or 30-50 mg/kg body weight per day
  • Infants and Children upto 2 years: 500 mg in divided doses or 30-50 mg/kg body weight in divided doses

Interaction

Use with theophylline may increase serum levels and potential toxicity

Contraindications

Known hypersensitivity to Erythromycin

Side Effects

Allergic reactions, abdominal discomfort, nausea, vomiting

Pregnancy & Lactation

Caution advised due to crossing the placental barrier and excretion in breast milk

Precautions & Warnings

Given with care in patients with impaired hepatic function

Overdose Effects

Discontinue use, handle prompt elimination of unabsorbed drug

Therapeutic Class

Anti-diarrhoeal Antimicrobial drugs, Macrolides

Reconstitution

Direction for reconstitution of suspension provided

Storage Conditions

Keep below 25°C, away from light & moisture, out of reach of children

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