Ilocin 125 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Erythromycin oral |
| Company | Doctors chemical works ltd |
| Also available as |
Indications
- Upper respiratory tract infections
- Lower respiratory tract infections
- Ear infections
- Eye infections
- Skin and soft tissue infections
- Gastrointestinal tract infections
- Prophylaxis
- Osteomyelitis
- Diptheria
- Scarlet fever
- Cholecystitis
- Staphylococcal enterocolitis
Description
Belongs to the macrolides group of antibiotics
Micro-organisms Susceptible
- Gram positive: Cocci and bacilli
- Gram negative: Neisseria catarhalis, N.meningitis, N.gonorrhoea, Haemophilus influenzae, Brodetella, H. pertussis
- Other micro-organisms: Mycoplasma pneumoniae, Legionella pneumophila, Bacteroides fragilis, B.oralis, B.melaninogenicus, Fusobacterium, Chlamydia trachomatis, Treponema pallidum
Pharmacology
- Mode of Action: Interference with ribosomal protein synthesis
- Absorption: Destroyed by acid, stable ester form
- Blood Concentration: Peak serum concentrations 0.9 to 1.4 or 0.4 to 1.8 mg/ml
- Distribution: Widely distributed throughout body tissue and fluids
- Excretion: 5 to 15% excreted in urine, excreted in the bile
Dosage & Administration
- Adult and Children over 8 years: 250-500 mg every six hours for mild to moderate infections (may be increased for severe cases)
- Elderly: No special dosage recommendation
- Children aged 2 to 8 years: 250 mg every six hours or 30-50 mg/kg body weight per day
- Infants and Children upto 2 years: 500 mg in divided doses or 30-50 mg/kg body weight in divided doses
Interaction
Use with theophylline may increase serum levels and potential toxicity
Contraindications
Known hypersensitivity to Erythromycin
Side Effects
Allergic reactions, abdominal discomfort, nausea, vomiting
Pregnancy & Lactation
Caution advised due to crossing the placental barrier and excretion in breast milk
Precautions & Warnings
Given with care in patients with impaired hepatic function
Overdose Effects
Discontinue use, handle prompt elimination of unabsorbed drug
Therapeutic Class
Anti-diarrhoeal Antimicrobial drugs, Macrolides
Reconstitution
Direction for reconstitution of suspension provided
Storage Conditions
Keep below 25°C, away from light & moisture, out of reach of children