Makcin 125 mg/5 ml (Powder for Suspension)
Medicine Details
| Category | Details |
|---|---|
| Generic | Erythromycin oral |
| Company | Techno drugs ltd |
Indications
- Treatment of upper respiratory tract infections
- Treatment of lower respiratory tract infections
- Treatment of ear infections
- Treatment of eye infections
- Treatment of skin and soft tissue infections
- Treatment of gastrointestinal tract infections
- Prophylactic use
- Treatment of other infections
Description
Belongs to the macrolides group of antibiotics. Bacteriostatic or bactericidal action. Used for infections caused by penicillinase producing staphylococci. Susceptible to various micro-organisms including gram (+)ve and gram (-)ve bacteria, mycoplasmas, and chlamydia.
Pharmacology
- Inhibits microsomal protein synthesis
- Specific binding to 50S subunit or 70S ribosome
- Active against Grampositive bacteria and Gram-negative bacteria
- Absorption and blood concentration
- Distribution in body tissue and fluids
- Excretion in urine and bile
Dosage & Administration
- Dosage for adults and children over 8 years
- Dosage for elderly
- Dosage for children aged 2 to 8 years
- Dosage for infants and children up to 2 years
Interaction
Potential interaction with theophylline leading to increased serum levels and toxicity
Contraindications
Known hypersensitivity to Erythromycin
Side Effects
- Rare allergic reactions
- Mild abdominal discomfort
- Nausea and vomiting after oral administration
Pregnancy & Lactation
No evidence of teratogenicity or toxicity in human studies. Caution in pregnant and lactating patients.
Precautions & Warnings
Careful use in patients with impaired hepatic function
Overdose Effects
Prompt discontinuation in case of overdosage. Prompt elimination of unabsorbed drug.
Therapeutic Class
Anti-diarrhoeal Antimicrobial drugs, Macrolides
Reconstitution
Directions for reconstitution of suspension. Storage instructions for reconstituted suspension.
Storage Conditions
Store below 25°C, away from light and moisture. Keep out of the reach of children.