Mitrocin 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 60.00

Medicine Details

Category Details
Generic Erythromycin oral
Company Millat pharmaceuticals ltd
Also available as
Mitrocin 250 mg tablet Mitrocin 500 mg tablet Mitrocin ds 250 mg suspension

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of ear infections
  • Treatment of eye infections
  • Treatment of skin and soft tissue infections
  • Treatment of gastrointestinal tract infections
  • Prophylaxis for pre and post-operative, trauma, burns, rheumatic fever
  • Treatment of osteomyelitis
  • Treatment of diptheria
  • Treatment of scarlet fever
  • Treatment of whooping cough

Description

  • Belongs to macrolides group of antibiotics
  • Exerts bacteriostatic or bactericidal action based on interference with ribosomal protein synthesis within bacterial cell
  • Effective against penicillinase producing staphylococci
  • Susceptible to gram positive and gram negative micro-organisms

Pharmacology

  • Inhibits microsomal protein synthesis in susceptible organisms by inhibiting the translocation process
  • Active against many gram positive bacteria, some gram negative bacteria, mycoplasmas, and chlamydia
  • Destroyed by acid, but stable ester form is administered
  • Widely distributed throughout body tissue and fluids

Dosage & Administration

  • Adult dose: 250-500 mg every six hours for mild to moderate infections, may increase in severe cases
  • Elderly dose: No special recommendation, administered three times daily or twice daily
  • Children aged 2 to 8 years: 30-50 mg/kg body weight per day divided into four equal dosages
  • Infants and children upto 2 years: 30-50 mg/kg body weight in divided doses

Interaction

  • Potential increase of serum theophylline levels and theophylline toxicity
  • May need to reduce theophylline dose when using Mitrocin

Contraindications

  • Known hypersensitivity to Erythromycin

Side Effects

  • Rare allergic reactions, mild anaphylaxis
  • Occasional abdominal discomfort, nausea, and vomiting after oral administration

Pregnancy & Lactation

  • No evidence of teratogenicity or toxicity in humans
  • Caution should be exercised during pregnancy and lactation as it crosses the placental barrier and excreted in breast milk

Precautions & Warnings

  • Given with care in patients with impaired hepatic function as it is excreted principally in the bile

Overdose Effects

  • Discontinue in case of overdosage
  • Prompt elimination of unabsorbed drug is recommended
  • Not removed by peritoneal dialysis or haemodialysis

Therapeutic Class

  • Anti-diarrhoeal
  • Antimicrobial drugs
  • Macrolides

Reconstitution

  • Directions for reconstitution of suspension
  • Shake the bottle to loosen powder
  • Add boiled and cooled water to the dry powder of the bottle
  • Shake well after each addition until all the powder is in suspension
  • Reconstituted suspension should be stored in a cool and dry place, preferably in refrigerator

Storage Conditions

  • Keep below 25°C temperature, away from light and moisture
  • Keep out of the reach of children

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