Mitrocin DS 250 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 103.00

Medicine Details

Category	Details
Generic	Erythromycin oral
Company	Millat pharmaceuticals ltd
Also available as	Mitrocin 250 mg tablet Mitrocin 500 mg tablet Mitrocin 125 mg suspension

Title

Mitrocin DS

Description

Belongs to the macrolides group of antibiotics
Exerts bacteriostatic or bactericidal action based on specific interference with ribosomal protein synthesis
Effective against a wide variety of clinical infections
Particularly susceptible to Gram (+)ve : Cocci and bacilli, Gram (-)ve: Neisseria catarhalis, N.meningitis, N.gonorrhoea, Haemophilus influenzae
Effective against Mycoplasma pneumoniae, Legionella pneumophila, Bacteroides fragilis, B.oralis, B.melaninogenicus, Fusobacterium, Chlamydia trachomatis, Treponema pallidum

Indications

Treatment of upper respiratory tract infections
Treatment of lower respiratory tract infections
Treatment of ear infections
Treatment of eye infections
Treatment of skin and soft tissue infections
Treatment of gastrointestinal tract infections
Prophylaxis for pre and post-operative, trauma, burns, rheumatic fever
Treatment of other infections like osteomyelitis, diphtheria, scarlet fever, whooping cough

Pharmacology

Mechanism of action: Inhibits microsomal protein synthesis by inhibiting the translocation process
Activity: Active against many Gram-positive bacteria, some Gram-negative bacteria, mycoplasmas, and chlamydia
Absorption: Administered in the form of stable ester to avoid destruction by acid
Blood concentration: Peak serum concentrations attained in 1 to 4 hours after an oral dose
Distribution: Widely distributed throughout body tissue and fluids
Excretion: 5 to 15% of the dose excreted in the urine, excreted in the bile

Dosage administration

Adults and Children over 8 years: 250-500 mg every six hours for mild to moderate infections
Elderly: No special dosage recommendation
Children aged 2 to 8 years: 250 mg every six hours or 30-50 mg/kg body weight per day
Infants and Children up to 2 years: Dosage based on body weight

Interaction

May increase serum theophylline levels and potential theophylline toxicity when used in patients receiving high dosage of theophylline

Contraindications

Known hypersensitivity to Erythromycin

Side effects

Rare allergic reactions, mild anaphylaxis
Abdominal discomfort, nausea, vomiting after oral administration

Pregnancy lactation

Caution should be exercised when prescribing to pregnant patients and lactating mothers

Precautions warnings

Given with care in patients with impaired hepatic function

Overdose effects

Discontinue if overdosed; not removed by peritoneal dialysis or haemodialysis

Therapeutic class

Anti-diarrhoeal Antimicrobial drugs, Macrolides

Reconstitution

Reconstitute suspension with boiled and cooled water, store in a cool and dry place, discard unused portion after 7 days

Storage conditions

Keep below 25°C temperature, away from light & moisture, keep out of the reach of children