Eryth 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 55.00

Medicine Details

Category Details
Generic Erythromycin oral
Company Marksman pharmaceuticals ltd

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Ear infections
  • Eye infections
  • Skin and Soft tissue infections
  • Gastrointestinal tract infections
  • Prophylaxis
  • Other infections

Description

Eryth belongs to the macrolides group of antibiotics.

Pharmacology

  • Mode of Action: Inhibition of microsomal protein synthesis
  • Specific Binding:
    • 50S subunit
    • 70S ribosome
  • Activity Against:
    • Gram-positive bacteria
    • Gram-negative bacteria
    • Mycoplasmas
    • Chlamydia
  • Absorption: Destroyed by acid, stearate hydrolyzed in the intestine
  • Blood Concentration: Peak serum concentrations attained in 1 to 4 hours
  • Distribution:
    • Widely distributed throughout body tissue and fluids
    • Retention in the liver and spleen
    • Enters the cerebrospinal fluid
    • Crosses the placenta and excreted in the milk
  • Excretion: 5 to 15% excreted in the urine, large amounts excreted in the bile

Dosage & Administration

  • Adult and Children over 8 years: 250-500 mg every six hours for mild to moderate infections
  • Elderly: No special dosage recommendation
  • Children aged 2 to 8 years: 250 mg every six hours or 30-50 mg/kg body weight per day divided into four equal dosage
  • Infants and Children upto 2 years: 500 mg in divided doses or 30-50 mg/kg body weight in divided doses

Interaction

Increase of serum theophylline levels and potential theophylline toxicity

Contraindications

Known hypersensitivity to Erythromycin

Side Effects

  • Allergic reactions
  • Abdominal discomfort
  • Nausea
  • Vomiting

Pregnancy & Lactation

Excretion in breast milk, caution in pregnant patients and lactating mothers

Precautions & Warnings

Given with care in patients with impaired hepatic function

Overdose Effects

Discontinued in case of overdosage

Therapeutic Class

Anti-diarrhoeal Antimicrobial drugs, Macrolides

Reconstitution

Direction for reconstitution of suspension provided

Storage Conditions

Keep below 25°C temperature, away from light & moisture, Keep out of the reach of children

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