Adiz 500 mg (Tablet)
Unit Price: ৳ 45.00 (3 x 4: ৳ 540.00)
Strip Price: ৳ 180.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Azithromycin dihydrate |
| Company | Euro pharma ltd |
| Also available as |
Title
- Adiz 500 mg Tablet
Categories
- Antibiotics
- Macrolide Antibiotics
Description
- Adiz is indicated for infections (caused by susceptible organisms) in lower respiratory tract infections including bronchitis and pneumonia, in upper respiratory tract infections including sinusitis and pharyngitis/tonsillitis, in otitis media, and in skin and soft tissue infections. In sexually transmitted diseases in men and women, Adiz is indicated in the treatment of non-gonococcal urethritis and cervicitis due to Chlamydia trachomatis.
Dosage
- Oral - Adult: 500 mg once daily orally for 3 days or 500 mg once on day 1, then 250 mg once on days 2-5 for 4 days.
- For sexually transmitted diseases caused by Chlamydia trachomatis in adults, the dose is 1 gm given as a single dose or 500 mg once on day 1, followed by 250 mg once daily for next 2 days may also be given.
- Children: 10 mg/kg body weight once daily for 3 days for child over 6 months.
Mode of Action
- Azithromycin acts by binding to the 50S ribosomal subunit of susceptible microorganisms and, thus, interfering with microbial protein synthesis.
Pharmacology
- Azithromycin is acid-stable and can therefore be taken orally with no need of protection from gastric acids.
Interaction
- Antacid: Azithromycin should be taken at least 1 hour before or 2 hours after the antacid.
- Carbamazepine: No significant effect was observed on the plasma levels of carbamazepine or its active metabolite.
- Cyclosporin: Caution should be exercised before co-administration of these two drugs. If coadministrations is necessary, cyclosporin levels should be monitored.
- Digoxin: In patients receiving concomitant azithromycin and digoxin the possibility of raised digoxin levels should be borne in mind and digoxin levels monitored.
Contraindications
- Azithromycin is contraindicated in patients hypersensitive to Azithromycin or any other macrolide antibiotic.
Side Effects
- Most side-effects observed were mild to moderate in severity. The majority of side-effects were gastrointestinal in origin with nauseas, abdominal discomfort, vomiting, flatulence, diarrhea and loose stools being occasionally observed.
Pregnancy & Lactation
- Pregnancy Category of Azithromycin is B. Animal reproduction studies have demonstrated that Azithromycin has no evidence of harm to the fetus.
- Caution should be exercised when Azithromycin is administered to nursing women.
Precautions & Warnings
- Rare serious allergic reactions, including angioneurotic oedema and anaphylaxis, have been reported.
Overdose Effects
- Typical symptoms of overdosage with macrolide antibiotics include hearing loss, severe nausea, vomiting and diarrhea.
Storage Conditions
- Keep in a dry place away from light and heat. Keep out of the reach of children.
Chemical Structure
- Molecular Formula : C38H72N2O12
Reconstitution Procedure of Suspension
- Shake the bottle well to loosen the powder, Add boiled and cooled water up to the water mark of the bottle label, Shake until powder is completely mixed with water.
Administration
- Azithromycin should be taken at least 1 hour before or 2 hours after meal.
Use in Special Populations
- No dose adjustment is needed in patients with mild renal impairment (creatinine clearance >40 ml/min), but there are no data regarding azithromycin in patients with more severe renal impairment, thus caution should be exercised in using azithromycin in these patients.
- As the liver is the principal route of excretion of azithromycin, it should not be used in patients with hepatic disease.
Effect on Ability to Drive and Use Machines
- There is no evidence to suggest that azithromycin may have an effect on a patient’s ability to drive or operate machinery.
Common Questions
- Adiz 500 mg Tablet performs its action by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.
- Adiz 500 mg Tablet is used for the treatment and prevention of community-acquired pneumonia, pharyngitis/tonsillitis, and skin and soft tissue infections.
- Adverse effects include diarrhea, dry or scaly skin, abdominal pain, difficult or painful urination, vomiting, fever, and acid or sour stomach.
- Adiz 500 mg Tablet should be kept in a cool dry place and its original packaging. Make sure this medication remains unreachable to children and pets. The patient should consult a doctor for its further uses.
- The use of Adiz 500 mg Tablet can cause diarrhea. It is an antibiotic that kills harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea.
- Adiz 500 mg Tablet is safe if used at prescribed doses as advised by your doctor.
- Adiz 500 mg Tablet is an antibiotic that belongs to a class of antibiotics known as macrolides.
- You should inform your doctor if you do not notice any improvement in your symptoms after 3 days of taking Adiz 500 mg Tablet and if your symptoms get worse.