Adiz 200 mg/5 ml (Powder for Suspension)
15 ml bottle: ৳ 95.00
Medicine Details
Category | Details |
---|---|
Generic | Azithromycin dihydrate |
Company | Euro pharma ltd |
Also available as |
Title
- Adiz 200 mg/5 ml Suspension
Categories
- Medicine
- Antibiotic
Description
- Indicated for infections in lower respiratory tract, upper respiratory tract, otitis media, skin and soft tissue infections, and sexually transmitted diseases
- Pharmacologically active against various microorganisms including gram-positive and gram-negative bacteria
- Available in oral form for adults and children, and also as an injection for IV infusion in adults
- Reconstitution procedure for oral suspension and administration instructions for oral intake
- Interaction with antacids, carbamazepine, cyclosporin, digoxin, ergot derivatives, methylprednisolone, theophylline, warfarin, and terfenadine
- Contraindicated in patients hypersensitive to azithromycin, co-administration of ergot derivatives, and patients with hepatic diseases
- Well-tolerated with low incidence of side-effects, primarily gastrointestinal in origin
- Pregnancy Category B; caution in use during pregnancy and lactation, and in patients with renal or hepatic impairment
- No data on overdose effects; typical symptoms may include hearing loss, severe nausea, vomiting, and diarrhoea
- Storage requirements: dry place, away from light and heat, and out of the reach of children
- Molecular Formula: C38H72N2O12; Chemical Structure: [link to the chemical structure image]
- Common Questions about Adiz 200 mg/5 ml Suspension including its uses, side effects, storage, and safety precautions
Dosage
- Oral dosage for adults: 500 mg once daily for 3 days
- Oral dosage for children varies based on body weight and specific infections
- IV infusion dosage for community-acquired pneumonia and pelvic inflammatory disease in adults
- Oral intake instructions and reconstitution procedure for suspension
Mode of Action
- Stable and orally absorbable
- Acid-stable and greater absorption on an empty stomach
- Active transportation to the site of infection and high tissue concentrations
- Bacterial protein synthesis inhibition and nucleic acid synthesis unaffected
Microbiology
- Acts by binding to the 50S ribosomal subunit of susceptible microorganisms
Interaction
- Specific interactions with antacids, carbamazepine, cyclosporin, digoxin, and other drugs
- Caution exercised before co-administration of azithromycin with certain drugs
Contraindications
- Hypersensitivity to azithromycin or other macrolide antibiotics
- Co-administration with ergot derivatives
- Patients with hepatic diseases
Side Effects
- Mild to moderate gastrointestinal side-effects
- Rare cases of serious hypersensitivity reactions
- Elevations in liver transaminases and rare cases of cholestatic jaundice
- Transient mild reductions in neutrophil counts and reversible hearing impairment
Pregnancy & Lactation
- Pregnancy Category B; no evidence of harm to the fetus in animal studies
- Caution advised in pregnant and nursing women
Precautions & Warnings
- Rare reports of serious allergic reactions including angioneurotic oedema and anaphylaxis
Use in Special Populations
- No dose adjustment needed in patients with mild renal impairment
- Not recommended in patients with hepatic impairment
Overdose Effects
- No data available; typical symptoms include hearing loss, severe nausea, vomiting, and diarrhoea
Storage Conditions
- Keep in a dry place away from light and heat; out of the reach of children
Chemical Structure
- Molecular Formula: C38H72N2O12; Chemical Structure: [link to the chemical structure image]
Commonly Asked Questions
- Adiz 200 mg/5 ml Suspension performs its action by preventing bacterial protein synthesis
- Uses include treatment and prevention of community-acquired pneumonia, pharyngitis/tonsillitis, and skin and soft tissue infections
- Storage and disposal instructions, potential side effects, and precautions
- Safety, antibiotic classification, improvement timeline, and quick tips for usage