Amzith 200 mg/5 ml (Powder for Suspension)
30 ml bottle: ৳ 130.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Azithromycin dihydrate |
| Company | Amulet pharmaceuticals ltd |
| Also available as |
Title
- Amzith 200 mg/5 ml Suspension
Categories
- Medicine
- Antibiotic
- Macrolide
Dosage Form
- Oral Suspension
- Injection for IV Infusion
Indications
- Lower respiratory tract infections
- Upper respiratory tract infections
- Otitis media
- Skin and soft tissue infections
- Non-gonococcal urethritis
- Cervicitis
Pharmacology
- Oral absorption with no need for protection from gastric acids
- Time to peak concentration in adults
- High concentration in phagocytes
- Long half-life allowing large single dose administration
- Biliary excretion as a major elimination route
- Microbiological activity against various microorganisms
Adult Dosage
- 500 mg once daily orally for 3 days
- 500 mg once on day 1, then 250 mg once daily for 4 days
- 1 gm single dose for sexually transmitted diseases
Children Dosage
- 10 mg/kg body weight once daily for 3 days
- 200 mg for 3 days if 15-25 kg body weight
- 300 mg for 3 days if 26-35 kg body weight
- 400 mg for 3 days if 36-45 kg body weight
Administration Reconstitution
- Shake the bottle well to loosen the powder
- Add boiled and cooled water up to the water mark of the bottle label
- Shake until powder is completely mixed with water
Antacid Interaction
- Take at least 1 hour before or 2 hours after the antacid
Cyclosporin Interaction
- Caution should be exercised before co-administration
- Cyclosporin levels should be monitored and the dose adjusted accordingly
Digoxin Interaction
- Possibility of raised digoxin levels should be borne in mind and digoxin levels monitored
Ergot Derivatives Interaction
- Avoid co-administration due to the theoretical possibility of ergotism
Methylprednisolone Interaction
- Azithromycin has no significant effect on Methylprednisolone pharmacokinetics
Pregnancy Category
- Category B
Adverse Effects
- Gastrointestinal side-effects
- Allergic reactions
- Reversible elevations in liver transaminases
- Rare cases of cholestatic jaundice
- Transient mild reductions in neutrophil counts
- Reversible hearing impairment in high prolonged doses
Storage
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C38H72N2O12
Common Questions
- What is Amzith 200 mg/5 ml Syrup?
- What are the uses of Amzith 200 mg/5 ml Syrup?
- What are the Side Effects of Amzith 200 mg/5 ml Syrup?
- What are the instructions for storage and disposal Amzith 200 mg/5 ml Syrup?
- Can the use of Amzith 200 mg/5 ml Syrup cause diarrhea?
- Is Amzith 200 mg/5 ml Syrup safe?
- Is Amzith 200 mg/5 ml Syrup an antibiotic?
- What if I don't get better even after taking Amzith 200 mg/5 ml Syrup?
- Patient Tips
Use in Special Populations
- No dose adjustment needed in patients with mild renal impairment
- Caution in using azithromycin in patients with more severe renal impairment
- Caution in using azithromycin in patients with hepatic disease
Overdose Effects
- Typical symptoms include hearing loss, severe nausea, vomiting, and diarrhea
- Gastric lavage and general supportive measures are indicated
Contraindications
- Hypersensitivity to Azithromycin or any other macrolide antibiotic
- Co-administration of ergot derivatives
- Patients with hepatic diseases
Precautions & Warnings
- Rare serious allergic reactions reported with recurrent symptoms
- Caution required with long period of observation and treatment
Interaction
- Antacid
- Cyclosporin
- Digoxin
- Ergot derivatives
- Methylprednisolone
- Theophylline
- Warfarin
- Terfenadine
Pregnancy & Lactation
- Animal reproduction studies indicate no harm to the fetus
- Caution in pregnant women
- Caution when administered to nursing women
Pediatric Uses
- No dose adjustment needed in patients with mild renal impairment
- Caution in using azithromycin in patients with more severe renal impairment
- No effect on a patient's ability to drive or operate machinery