Asizith 500 mg (Tablet)
Unit Price: ৳ 35.00 (12's pack: ৳ 420.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Azithromycin dihydrate |
| Company | Asiatic laboratories ltd |
| Also available as |
Title
- Asizith 500 mg Tablet
Categories
- Medicine
- Antibiotic
Description
- Asizith is indicated for infections in lower respiratory tract, upper respiratory tract, otitis media, skin and soft tissue infections, and sexually transmitted diseases
- Azithromycin is acid-stable and can be taken orally with no need of protection from gastric acids
- Azithromycin has high concentration in phagocytes and active transport to the site of infection
- Asizith is available in oral dosage form and for IV infusion
- Azithromycin acts by binding to the 50S ribosomal subunit of susceptible microorganisms and interfering with microbial protein synthesis
- Recommended dosage for adults is 500 mg once daily orally for 3 days, and for children, the dosage varies with body weight and condition
- Reconstitution procedure of suspension involves shaking the bottle well and adding boiled and cooled water up to the water mark of the bottle label
- Interaction with antacids, carbamazepine, cyclosporin, digoxin, ergot derivatives, methylprednisolone, theophylline, warfarin, and terfenadine
- Azithromycin is contraindicated in patients hypersensitive to Azithromycin or any other macrolide antibiotic, co-administration of ergot derivatives, and patients with hepatic diseases
- Side effects include gastrointestinal issues, allergic reactions, reversible elevations in liver transaminases, cholestatic jaundice, and hearing impairment
- Pregnancy Category of Azithromycin is B, and caution should be exercised when administered to nursing women
- Rare serious allergic reactions, including angioneurotic oedema and anaphylaxis, have been reported
- Azithromycin should be used with caution in patients with renal impairment, and it should not be used in patients with hepatic disease
- There is no data on overdosage with Asizith, typical symptoms of overdosage with macrolide antibiotics include hearing loss, severe nausea, vomiting, and diarrhea
- Keep in a dry place away from light and heat, and out of the reach of children
Dimensions
Color Options
Functions
- Prevents the synthesis of essential proteins required by bacteria
Materials
- Azithromycin
Technical Specifications
- Molecular Formula: C38H72N2O12
- Oral and IV dosage forms available
Design Elements
- Chemical structure with molecular formula
- Reconstitution procedure of suspension
Usability Features
- No evidence of effect on a patient’s ability to drive or operate machinery
Indications
- Infections in lower respiratory tract
- Infections in upper respiratory tract
- Otitis media and skin and soft tissue infections
- Sexually transmitted diseases in men and women
Pharmacology
- Azithromycin is readily absorbed
- High concentration in phagocytes
- Actively transported to the site of infection
- Time to peak concentration in adults: 2.1 to 3.2 hours
- Plasma concentrations decline in a polyphasic pattern with a mean apparent plasma clearance of 630 mL/min
Dosage
- 500 mg once daily orally for 3 days for adults
- Dosage varies for children based on body weight and condition
- Recommended dosage for IV infusion in adult patients with community-acquired pneumonia
Administration
- Azithromycin should be taken at least 1 hour before or 2 hours after meal
Interaction
- Antacid
- Carbamazepine
- Cyclosporin
- Digoxin
- Ergot derivatives
- Methylprednisolone
- Theophylline
- Warfarin
- Terfenadine
Contraindications
- Hypersensitivity to Azithromycin or any other macrolide antibiotic
- Co-administration of ergot derivatives
- Patients with hepatic diseases
Side Effects
- Gastrointestinal issues
- Allergic reactions
- Elevations in liver transaminases
- Cholestatic jaundice
- Hearing impairment
Pregnancy & Lactation
- Pregnancy Category: B
- Caution should be exercised when administered to nursing women
Precautions & Warnings
- Rare serious allergic reactions reported
Use in Special Populations
- No dose adjustment needed in patients with mild renal impairment
- Caution should be exercised in using azithromycin in patients with severe renal impairment
- Not to be used in patients with hepatic disease
Overdose Effects
- Typical symptoms include hearing loss, severe nausea, vomiting, and diarrhea
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C38H72N2O12
- Chemical structure provided with image
Commonly Asked Questions
- Information on uses, side effects, storage, and disposal provided