Azilit 200 mg/5 ml (Powder for Suspension)

15 ml bottle: ৳ 85.00

Medicine Details

Category Details
Generic Azithromycin dihydrate
Company Desh pharmaceuticals ltd
Also available as
Azilit 500 mg tablet

Indications

  • Lower respiratory tract infections
  • Upper respiratory tract infections
  • Sinusitis
  • Pharyngitis/tonsillitis
  • Otitis media
  • Skin and soft tissue infections
  • Non-gonococcal urethritis
  • Cervicitis

Pharmacology

  • Oral administration
  • Rapid absorption
  • Higher absorption on an empty stomach
  • Time to peak concentration: 2.1 to 3.2 hours
  • High concentration in phagocytes
  • Large concentrations released during active phagocytosis
  • Over 50 times higher concentration in tissues than in plasma
  • Half-life: 68 hours
  • Biliary excretion as a major route of elimination
  • Microbial protein synthesis interference

Dosage

  • Adult dosage: 500 mg once daily orally for 3 days
  • Adult sexually transmitted diseases dosage: 1 gm as a single dose
  • Pediatric dosage: 10 mg/kg body weight once daily for 3 days

Administration

  • Reconstitution procedure for suspension
  • Should be taken at least 1 hour before or 2 hours after a meal

Interaction

  • Antacid interaction
  • Carbamazepine interaction
  • Cyclosporin interaction
  • Digoxin interaction
  • Ergot derivatives interaction
  • Methylprednisolone interaction
  • Theophylline interaction
  • Warfarin interaction
  • Terfenadine interaction

Contraindications

  • Hypersensitivity to Azithromycin or macrolide antibiotics
  • Co-administration of ergot derivatives
  • Patients with hepatic diseases

Side Effects

  • Gastrointestinal side-effects
  • Nausea
  • Abdominal discomfort
  • Vomiting
  • Diarrhoea
  • Allergic reactions
  • Reversible elevations in liver transaminases
  • Cholestatic jaundice
  • Transient mild reductions in neutrofil counts
  • Hearing impairment in prolonged use

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution in nursing women

Precautions & Warnings

  • Rare serious allergic reactions
  • Angioneurotic oedema
  • Anaphylaxis

Use in Special Populations

  • No dose adjustment in mild renal impairment patients
  • Caution in patients with severe renal impairment
  • Not to be used in patients with hepatic disease
  • No effect on patient's ability to drive or operate machinery

Overdose Effects

  • Typical symptoms of macrolide antibiotics overdosage
  • Gastric lavage and general supportive measures are indicated

Storage Conditions

  • Dry place
  • Away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C38H72N2O12

Common Questions

  • Action of Azilit 200 mg/5 ml Syrup
  • Uses of Azilit 200 mg/5 ml Syrup
  • Side Effects of Azilit 200 mg/5 ml Syrup
  • Storage and disposal
  • Diarrhea as a possible side effect
  • Safety of Azilit 200 mg/5 ml Syrup
  • Nature of Azilit 200 mg/5 ml Syrup as an antibiotic
  • Instructions for treatment completion and side effect monitoring
  • Quick Tips for Azilit 200 mg/5 ml Syrup

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