Azimex 500 mg (Tablet)
Unit Price: ৳ 35.15 (2 x 5: ৳ 351.50)
Strip Price: ৳ 175.75
Medicine Details
| Category | Details |
|---|---|
| Generic | Azithromycin dihydrate |
| Company | Drug international ltd |
| Also available as |
Title
- Azimex 500 mg Tablet
Categories
- Medicine
- Antibiotic
- Macrolide Antibiotic
- Prescription Medicine
- Infectious Disease Medicine
Description
- Indications for lower respiratory tract infections including bronchitis and pneumonia
- Indications for upper respiratory tract infections including sinusitis and pharyngitis/tonsillitis
- Indications for otitis media
- Indications for skin and soft tissue infections
- Indications for sexually transmitted diseases in men and women (Chlamydia trachomatis)
- Can be taken orally with no need for protection from gastric acids
- Readily absorbed with greater absorption on an empty stomach
- Time to peak concentration in adults is 2.1 to 3.2 hours for oral dosage forms
- High concentration in phagocytes leading to active transportation to the site of infection
- Active phagocytosis leads to large concentrations of the medicine being released
- Concentration in the tissues can be over 50 times higher than in plasma
- Half-life allows a large single dose to maintain bacteriostatic levels in the infected tissue for several days
- Plasma concentrations of azithromycin declined in a polyphasic pattern with a mean apparent plasma clearance of 630 mL/min and a terminal elimination half-life of 68 hours
- Approximately 6% of the administered dose appears as unchanged drug in urine
- Binds to the 50S ribosomal subunit of susceptible microorganisms interfering with microbial protein synthesis
- Active against various microorganisms including Staphylococcus aureus, Haemophilus influenzae, Chlamydia pneumoniae, Streptococci, and Mycoplasma pneumoniae
- Recommended dosage for adults and children in oral and intravenous forms
- Reconstitution procedure for suspension including shaking the bottle well and adding boiled and cooled water
- Interaction with antacids, carbamazepine, cyclosporin, digoxin, ergot derivatives, methylprednisolone, theophylline, warfarin, and terfenadine
- Contraindications for patients hypersensitive to the medicine, macrolide antibiotics, and those with hepatic diseases
- Low incidence of side effects including gastrointestinal discomfort, allergic reactions, reversible elevations in liver transaminases, and hearing impairment
- Pregnancy Category B with caution for use during pregnancy and lactation
- Rare serious allergic reactions reported with angioneurotic oedema and anaphylaxis
- No dose adjustment needed in patients with mild renal impairment; not recommended for patients with severe renal impairment or hepatic disease
- No data on overdosage; typical symptoms of overdosage with macrolide antibiotics include hearing loss, severe nausea, vomiting, and diarrhea
- Storage conditions include keeping the medicine in a dry place away from light and heat
- Chemical structure with molecular formula C38H72N2O12
- Common questions and answers about the medicine including uses, side effects, storage, and safety tips