Azin 250 mg (Capsule)
Unit Price: ৳ 25.08 (2 x 3: ৳ 150.48)
Strip Price: ৳ 75.24
Medicine Details
| Category | Details |
|---|---|
| Generic | Azithromycin dihydrate |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Infections in lower respiratory tract including bronchitis and pneumonia
- Infections in upper respiratory tract including sinusitis and pharyngitis/tonsillitis
- Otitis media
- Skin and soft tissue infections
- Non-gonococcal urethritis and cervicitis due to Chlamydia trachomatis
Pharmacology
- Readily absorbed
- Greater absorption on empty stomach
- Time to peak concentration in adults
- High concentration in phagocytes
- Actively transported to site of infection
- Prolonged terminal half-life
- Biliary excretion as major route of elimination
- Active against various microorganisms
- Acts by binding to the 50S ribosomal subunit of susceptible microorganisms
Dosage
- 500 mg once daily orally for 3 days for adults
- 500 mg once on day 1, then 250 mg once on days 2-5 for adults
- Variable dosages for children based on body weight
- 500 mg as a single daily dose by the intravenous route for at least two days
Administration
- Suspension reconstitution procedure
- Taken at least 1 hour before or 2 hours after meal
Interaction
- Interaction with antacids
- Pharmacokinetic interaction with carbamazepine
- Interference with metabolism of cyclosporin
- Effect on the metabolism of digoxin
- Theoretical possibility of ergotism
- Pharmacokinetic interaction with methylprednisolone
- Lack of evidence of pharmacokinetic interaction with theophylline
- Pharmacodynamic interaction with warfarin
- Minimal effect on pharmacokinetics of terfenadine
Contraindications
- Hypersensitivity to Azithromycin or macrolide antibiotics
- Co-administration with ergot derivatives
- Patients with hepatic diseases
Side Effects
- Low incidence of side-effects
- Majority of side-effects gastrointestinal in origin
- Allergic reactions such as rash or photosensitivity
- Reversible elevations in liver transaminases
- Rare cases of cholestatic jaundice
- Transient mild reductions in neutrophil counts
- Reversible hearing impairment in investigational studies
Pregnancy & Lactation
- Pregnancy Category B
- No evidence of harm to the fetus in animal studies
- Caution in use during pregnancy and lactation
Precautions & Warnings
- Rare serious allergic reactions reported
- Caution in using azithromycin in patients with severe renal impairment
Use in Special Populations
- No dose adjustment needed in patients with mild renal impairment
- Not to be used in patients with hepatic disease
- No evidence of effect on ability to drive or use machines
Overdose Effects
- Typical symptoms of overdosage with macrolide antibiotics
- Gastric lavage and general supportive measures indicated
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C38H72N2O12
Common Questions about Azin 250 mg Capsule
- Action of Azin 250 mg Capsule
- Uses of Azin 250 mg Capsule
- Side Effects of Azin 250 mg Capsule
- Storage and disposal instructions for Azin 250 mg Capsule
- Possible diarrhea as a side effect
- Safety of Azin 250 mg Capsule
- Azin 250 mg Capsule as an antibiotic
- What to do if no improvement with Azin 250 mg Capsule
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