Azi S 500 mg (Tablet)

Unit Price: ৳ 30.00 (6's pack: ৳ 180.00)

Medicine Details

Title

Azi S 500 mg Tablet

Categories

  • Antibiotic
  • Macrolide Antibiotic
  • Infection Treatment
  • Sexually Transmitted Disease Treatment

Description

Azi S is indicated for infections caused by susceptible organisms in lower respiratory tract infections, upper respiratory tract infections, otitis media, skin and soft tissue infections, and sexually transmitted diseases in men and women.

Dosage

  • 500 mg once daily orally for 3 days
  • 500 mg once on day 1, then 250 mg once on days 2-5 for 4 days
  • 1 gm as a single dose for sexually transmitted diseases caused by Chlamydia trachomatis

Administration

Azithromycin should be taken at least 1 hour before or 2 hours after meal; reconstitution procedure for suspension provided.

Mode of Action

  • Readily absorbed
  • High concentration in phagocytes
  • Binds to 50S ribosomal subunit of susceptible microorganisms
  • Interferes with microbial protein synthesis

Indications

  • Lower respiratory tract infections
  • Upper respiratory tract infections
  • Otitis media
  • Skin and soft tissue infections
  • Sexually transmitted diseases

Pharmacology

  • Time to peak concentration: 2.1 to 3.2 hours
  • Prolonged terminal half-life allowing large single dose administration
  • Active against various microorganisms

Interaction

  • Take at least 1 hour before or 2 hours after antacids
  • Exercise caution with co-administration of cyclosporine and digoxin
  • No significant effect on theophylline levels
  • Monitor warfarin levels if co-administered

Contraindications

  • Hypersensitivity to Azithromycin or macrolide antibiotics
  • Co-administration with ergot derivatives
  • Patients with hepatic diseases

Side Effects

  • Mild to moderate gastrointestinal side effects
  • Allergic reactions and photosensitivity
  • Rare cases of serious hypersensitivity reactions
  • Transient reductions in neutrofil counts
  • Reversible hearing impairment in some patients

Pregnancy & Lactation

  • Pregnancy Category B
  • Not known if secreted in breast milk
  • Caution advised during nursing

Precautions & Warnings

  • Rare serious allergic reactions reported
  • Exercise caution in patients with severe renal impairment
  • Avoid use in patients with hepatic disease

Use in Special Populations

  • No dose adjustment needed in mild renal impairment
  • Not recommended in patients with hepatic disease
  • No effect on ability to drive or use machines

Overdose Effects

Typical symptoms include hearing loss, severe nausea, vomiting, and diarrhea; gastric lavage and supportive measures indicated

Storage Conditions

Keep in a dry place away from light and heat; keep out of the reach of children

Chemical Structure

  • Molecular Formula: C38H72N2O12
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-100-azithromycin-dihydrate-chemical-structure-tFo4BQqfsRzQwcODCGo2.svg

Commonly Asked Questions

  • What is Azi S 500 mg Tablet?
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  • What are the Side Effects of Azi S 500 mg Tablet?
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  • Can the use of Azi S 500 mg Tablet cause diarrhea?
  • Is Azi S 500 mg Tablet safe?
  • Is Azi S 500 mg Tablet an antibiotic?
  • What if I don't get better even after taking Azi S 500 mg Tablet?
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