Azithrocin 250 mg (Capsule)

Unit Price: ৳ 25.00 (1 x 10: ৳ 250.00)
Strip Price: ৳ 250.00

Medicine Details

Category Details
Generic Azithromycin dihydrate
Company Beximco pharmaceuticals ltd
Also available as
Azithrocin 500 mg tablet Azithrocin 200 mg suspension Azithrocin 500 mg injection Azithrocin 250 mg tablet

Title

  • Azithrocin 250 mg Capsule

Categories

  • Medicine
  • Antibiotic
  • Macrolide

Description

  • Azithrocin is used to treat various infections caused by susceptible organisms, such as lower respiratory tract infections, upper respiratory tract infections, otitis media, skin and soft tissue infections, and certain sexually transmitted diseases in men and women. It is also used for community-acquired pneumonia, pharyngitis/tonsillitis, and prevention of bacterial protein synthesis.

Dosage

  • 500 mg once daily orally for 3 days in adults; 10 mg/kg body weight once daily for 3 days for children over 6 months; 500 mg (2½ teaspoonfuls) once daily for 7-10 days in typhoid fever; 500 mg as a single daily dose by the intravenous route for at least two days in adults with community-acquired pneumonia.

Pharmacology

  • Readily absorbed; greater absorption on an empty stomach; time to peak concentration in adults is 2.1 to 3.2 hours; actively transported to the site of infection; large concentrations released during active phagocytosis; high concentration in tissues; half-life allows large single dose administration.

Administration

  • Reconstitution procedure for suspension: Add boiled and cooled water to the water mark, shake until powder is mixed with water; should be taken at least 1 hour before or 2 hours after a meal.

Interaction

  • Caution when co-administered with antacids, carbamazepine, cyclosporin, digoxin, ergot derivatives, methylprednisolone, theophylline, warfarin, and terfenadine.

Contraindications

  • Contraindicated in patients hypersensitive to Azithromycin or any other macrolide antibiotic; co-administration of ergot derivatives; patients with hepatic diseases.

Indications

  • Indicated for infections caused by susceptible organisms in various respiratory tract infections, otitis media, skin and soft tissue infections, and sexually transmitted diseases in men and women.

Storage

  • Keep in a dry place away from light and heat; keep out of the reach of children.

Side Effects

  • Mild to moderate gastrointestinal side-effects; allergic reactions such as rash or photosensitivity; reversible elevations in liver transaminases; rare cases of cholestatic jaundice; transient mild reductions in neutrophil counts; reversible hearing impairment in some patients.

Pregnancy & Lactation

  • Pregnancy Category B; caution during pregnancy if adequate alternatives are not available; caution during breastfeeding.

Warnings

  • Rare serious allergic reactions reported; caution in patients with renal impairment; not recommended in patients with severe hepatic impairment.

Overdose Effects

  • Typical symptoms may include hearing loss, severe nausea, vomiting, and diarrhea; gastric lavage and general supportive measures are indicated.

Chemical Structure

  • Molecular Formula: C38H72N2O12; Chemical Structure: (Image of chemical structure).

Common Questions

  • Azithrocin 250 mg Capsule performs its action by preventing the synthesis of essential proteins required by bacteria.
  • Used for the treatment and prevention of community-acquired pneumonia, pharyngitis/tonsillitis, and skin and soft tissue infections.
  • Side effects include diarrhea, dry or scaly skin, abdominal pain, difficult or painful urination, vomiting, fever, acid or sour stomach, aggression or anger, excessive air or gas in the stomach, and heartburn.
  • Should be kept in a cool dry place and its original packaging; the patient should consult a doctor for further uses.
  • May cause diarrhea due to effect on helpful bacteria in the stomach or intestine; consult doctor if experiencing severe diarrhea.
  • Safe if used at prescribed doses as advised by the doctor.
  • Belongs to a class of antibiotics known as macrolides; may not improve symptoms after 3 days.
  • Do not skip doses; finish the full course of treatment; take 1 hour before or 2 hours after food; avoid taking antacids 2 hours before or after; monitor for severe side effects.

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