Azomac 200 mg/5 ml (Powder for Suspension)

Indications

• Lower respiratory tract infections treatment
• Upper respiratory tract infections treatment
• Otitis media treatment
• Skin and soft tissue infections treatment
• Treatment of non-gonococcal urethritis
• Treatment of cervicitis due to Chlamydia trachomatis

Pharmacology

• Acid-stable for oral administration
• Readily absorbed
• Time to peak concentration in adults: 2.1 to 3.2 hours
• High concentration in phagocytes for active transport to infection site
• Over 50 times higher concentration in tissues compared to plasma
• Biliary excretion as major elimination route

Dosage

• Adult oral dosage: 500 mg once daily for 3 days
• Child dosage based on body weight
• Oral dose followed by IV infusion
• Recommended dose for community-acquired pneumonia

Administration

• Suspension reconstitution steps
• Take at least 1 hour before or 2 hours after meal

Interaction

• Take azithromycin 1 hour before or 2 hours after antacids
• Potential interactions with various medications like cyclosporin and digoxin

Contraindications

• Hypersensitivity to Azithromycin
• Contraindicated in patients with hepatic diseases

Side Effects

• Mainly gastrointestinal side effects
• Allergic reactions like rash
• Reversible elevations in liver transaminases
• Rare cases of cholestatic jaundice

Pregnancy & Lactation

• Pregnancy Category B
• Caution in nursing women
• Animal studies show no harm to fetus

Precautions & Warnings

• Risk of serious allergic reactions
• Long period of observation and treatment in some cases

Use in Special Populations

• No dose adjustment in mild renal impairment
• Avoid use in severe renal impairment and hepatic impairment
• No effect on ability to drive or use machinery

Overdose Effects

• Typical symptoms include hearing loss and gastrointestinal issues
• Gastric lavage and general supportive measures recommended

Storage Conditions

• Keep in dry place away from light and heat
• Keep out of reach of children

Chemical Structure

• Molecular Formula: C38H72N2O12

Common Questions about Azomac 200 mg/5 ml Suspension

• Information about syrup's action and uses
• Common side effects
• Storage and disposal instructions
• Caution regarding diarrhea
• Safety at prescribed doses
• Belongs to class of macrolide antibiotics
• Instructions for lack of improvement in symptoms

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