Curazith 200 mg/5 ml (Powder for Suspension)

15 ml bottle: ৳ 85.26

Medicine Details

Title

  • Curazith 200 mg/5 ml Suspension

Categories

  • Medicine
  • Antibiotic

Description

  • Indicated for infections in lower respiratory tract, upper respiratory tract, otitis media, and skin and soft tissue infections
  • Pharmacologically absorbed orally, with high concentration in phagocytes and actively transported to the site of infection
  • Bacteriostatic levels maintained in infected tissue for several days
  • Adult dosage of 500 mg once daily orally for 3 days
  • Well tolerated with low incidence of side-effects
  • Pregnancy Category B, caution suggested during lactation
  • Administered orally, reconstitution procedure for suspension
  • Contraindicated in patients hypersensitive to azithromycin or macrolide antibiotics
  • No dose adjustment needed in patients with mild renal impairment
  • No data on overdose effects with Curazith
  • Storage - keep in dry place away from light and heat

Dimensions

  • 200 mg/5 ml

Color options

  • White

Functions

  • Prevention of community-acquired pneumonia, pharyngitis/tonsillitis, and skin and soft tissue infections

Materials

  • Azithromycin
  • Macrolide antibiotics

Technical specifications

  • Absorption time: 2.1 to 3.2 hours
  • Plasma clearance: 630 mL/min
  • Elimination half-life: 68 hours
  • Reversible elevations in liver transaminases observed

Design elements

  • Chemical Structure: C38H72N2O12
  • Chemical structure image available

Usability features

  • Oral administration
  • Reconstitution procedure for suspension
  • No effect on ability to drive or use machines

Indications

  • Infections in lower and upper respiratory tract, otitis media, skin and soft tissue infections

Pharmacology

  • Acid-stable and can be taken orally
  • Peak concentration in adults: 2.1 to 3.2 hours
  • Actively transported to site of infection
  • Bacteriostatic levels maintained in infected tissue for several days
  • Active against most isolates of various microorganisms

Dosage

  • Adult dosage: 500 mg once daily orally for 3 days
  • Children dosage based on body weight
  • Injection for IV infusion in adult patients

Administration

  • Reconstitution procedure for suspension
  • Should be taken at least 1 hour before or 2 hours after meal

Interaction

  • Pharmacokinetic interactions with antacids, carbamazepine, cyclosporin, digoxin, ergot derivatives, methylprednisolone, theophylline, warfarin, terfenadine
  • Caution suggested for co-administration with certain medications

Contraindications

  • Hypersensitivity to azithromycin or macrolide antibiotics
  • Co-administration with ergot derivatives
  • Hepatic diseases

Side Effects

  • Mild to moderate gastrointestinal side-effects
  • Allergic reactions such as rash or photosensitivity
  • Reversible elevations in liver transaminases
  • Cholestatic jaundice observed rarely
  • Transitory mild reductions in neutrofil counts
  • Reversible hearing impairment observed in some patients

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution suggested during lactation

Precautions & Warnings

  • Rare serious allergic reactions reported
  • Long period of observation and treatment required for certain allergic reactions

Use in Special Populations

  • No dose adjustment needed in patients with mild renal impairment
  • Caution suggested in patients with severe renal impairment
  • Contraindicated in patients with hepatic disease
  • No effect on ability to drive or use machines

Overdose Effects

  • Typical symptoms of overdosage with macrolide antibiotics

Storage Conditions

  • Keep in dry place away from light and heat

Compound Summary

  • Molecular Formula: C38H72N2O12
  • Chemical Structure image available

Common Questions

  • What is Curazith 200 mg/5 ml Syrup?
  • What are the uses of Curazith 200 mg/5 ml Syrup?
  • What are the Side Effects of Curazith 200 mg/5 ml Syrup?
  • Instructions for storage and disposal
  • Can cause diarrhea
  • Safety at prescribed doses
  • Belongs to class of antibiotics known as macrolides
  • Inform doctor if no improvement after 3 days of treatment

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