Demacro 200 mg/5 ml (Powder for Suspension)

15 ml bottle: ৳ 85.00

Medicine Details

Category Details
Generic Azithromycin dihydrate
Company Decent pharma laboratories ltd
Also available as
Demacro 500 mg tablet

Title

  • Demacro 200 mg/5 ml Syrup

Categories

  • Antibiotics
  • Macrolide Antibiotic
  • Infection Treatment
  • Respiratory Tract Infection
  • Skin Infection
  • Sexually Transmitted Disease Treatment
  • Pediatric Medication

Indications

  • Lower Respiratory Tract Infections
  • Upper Respiratory Tract Infections
  • Otitis Media
  • Sinusitis
  • Pharyngitis/Tonsillitis
  • Non-Gonococcal Urethritis
  • Cervicitis

Pharmacology

  • Oral Administration
  • Absorption on Empty Stomach
  • High Concentration in Phagocytes
  • Active Transport to Site of Infection
  • Long Half-Life
  • Biliary Excretion
  • Phagocytosis
  • Protein Synthesis Inhibition
  • Microbial Protein Synthesis Interference
  • Ion Trapping
  • High Lipid Solubility
  • Peak Concentration Time
  • Polyphasic Pattern

Dosage

  • 500 mg Adult Oral Dose for 3 Days
  • 500 mg Day 1, then 250 mg Days 2-5
  • 1 gm Single Dose for Chlamydia trachomatis
  • 10 mg/kg Body Weight for 3 Days for Child over 6 Months
  • 200 mg for 15-25 kg Body Weight for 3 Days
  • 300 mg for 26-35 kg Body Weight for 3 Days
  • 400 mg for 36-45 kg Body Weight for 3 Days
  • 500 mg Once Daily for 7-10 Days in Typhoid Fever
  • 500 mg Adult IV Dose for Community-Acquired Pneumonia
  • 250 mg Adult Oral Dose for Pelvic Inflammatory Disease
  • IV Infusion Only
  • Oral Route Switch
  • Pediatric Dosing
  • Intravenous Therapy
  • Clinical Response Timing

Administration

  • Reconstitution Procedure for Suspension
  • Shake Bottle Well
  • Add Boiled and Cooled Water
  • Shake until Powder is Completely Mixed
  • Take at Least 1 Hour Before or 2 Hours After Meal

Interaction

  • Antacid Interaction
  • Carbamazepine Interaction
  • Cyclosporin Interaction
  • Digoxin Interaction
  • Ergot Derivatives Interaction
  • Methylprednisolone Interaction
  • Theophylline Interaction
  • Warfarin Interaction
  • Terfenadine Interaction

Contraindications

  • Hypersensitivity to Azithromycin or Macrolide Antibiotics
  • Co-administration with Ergot Derivatives
  • Hepatic Diseases

Side effects

  • Gastrointestinal Side Effects
  • Nausea
  • Abdominal Discomfort
  • Vomiting
  • Flatulence
  • Diarrhea
  • Loose Stools
  • Allergic Reactions
  • Rash
  • Photosensitivity
  • Hypersensitivity Reactions
  • Elevations in Liver Transaminases
  • Cholestatic Jaundice
  • Neutrophil Counts Reduction
  • Hearing Impairment
  • Reversible Hearing Impairment

Pregnancy and lactation

  • Pregnancy Category B
  • Animal Reproduction Studies
  • No Evidence of Harm to Fetus
  • Use During Pregnancy with Caution
  • No Adequate and Well-Controlled Studies in Pregnant Women
  • Unknown Secretion in Breast Milk
  • Caution in Nursing Women

Precautions and warnings

  • Allergic Reactions Similar to Erythromycin and Macrolides
  • Serious Allergic Reactions
  • Angioneurotic Oedema
  • Anaphylaxis
  • Recurrent Symptoms
  • Period of Observation
  • Renal Impairment
  • Hepatic Impairment
  • Effects on Ability to Drive and Use Machines

Special populations

  • No Dose Adjustment in Mild Renal Impairment
  • Caution in Severe Renal Impairment
  • Effect in Hepatic Impairment
  • No Effect on Ability to Drive or Operate Machinery

Overdose effects

  • Typical Symptoms
  • Hearing Loss
  • Severe Nausea
  • Vomiting
  • Diarrhea
  • Gastric Lavage
  • General Supportive Measures

Storage conditions

  • Dry Place
  • Away from Light and Heat
  • Out of Reach of Children

Chemical structure

  • Molecular Formula
  • C38H72N2O12
  • Chemical Structure Image

Commonly asked questions

  • Action of Demacro 200 mg/5 ml Syrup
  • Uses
  • Side Effects
  • Storage and Disposal Instructions
  • Diarrhea Causes
  • Safety
  • Antibiotic Classification
  • Consultation for Lack of Improvement
  • Quick Tips

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