Odazin 500 mg (Tablet)
Unit Price: ৳ 30.00 (12's pack: ৳ 360.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Azithromycin dihydrate |
| Company | Bengal drugs ltd |
Indications
- Lower respiratory tract infections
- Upper respiratory tract infections
- Skin and soft tissue infections
- Pharyngitis/tonsillitis
- Otitis media
- Non-gonococcal urethritis
- Cervicitis
Pharmacology
- Oral administration
- Absorption on empty stomach
- Time to peak concentration
- High concentration in phagocytes
- Active transport to site of infection
- Release of large concentrations during phagocytosis
- High concentration in tissues
- Ion trapping
- High lipid solubility
- Biliary excretion
- Microbial protein synthesis interference
- Active against gram-positive microorganisms
- Active against gram-negative microorganisms
- Active against Chlamydia pneumoniae
- Active against Mycoplasma pneumoniae
- High concentrations in plasma
Dosage
- 500 mg once daily orally for adults
- 500 mg once on day 1, then 250 mg once on days 2-5 for adults
- 1 gm single dose for Chlamydia trachomatis in adults
- 500 mg once on day 1, followed by 250 mg once daily for next 2 days for Chlamydia trachomatis in adults
- 10 mg/kg body weight once daily for children over 6 months
- 200 mg for 3 days for children 15-25 kg body weight
- 300 mg for 3 days for children 26-35 kg body weight
- 400 mg for 3 days for children 36-45 kg body weight
- 500 mg once daily for 7-10 days in typhoid fever
Administration
- Reconstitution of suspension
- Shaking the bottle well
- Adding boiled and cooled water
- Shaking until powder is completely mixed with water
- Taking at least 1 hour before or 2 hours after meal
Interaction
- Antacid interaction
- Carbamazepine interaction
- Cyclosporin interaction
- Digoxin interaction
- Ergot derivatives interaction
- Methylprednisolone interaction
- Theophylline interaction
- Warfarin interaction
- Terfenadine interaction
Contraindications
- Hypersensitivity to Azithromycin
- Hypersensitivity to macrolide antibiotic
- Co-administration of ergot derivatives
- Hepatic diseases
Side Effects
- Gastrointestinal side-effects
- Nausea
- Abdominal discomfort
- Vomiting
- Flatulence
- Diarrhoea
- Allergic reactions
- Rash
- Photosensitivity
- Elevations in liver transaminases
- Cholestatic jaundice
- Reductions in neutrophil counts
- Reversible hearing impairment
Pregnancy & Lactation
- Pregnancy category B
- No evidence of harm to fetus in animal studies
- No adequate and well controlled studies in pregnant women
- Use during pregnancy if adequate alternatives are not available
- Caution during lactation
Precautions & Warnings
- Rare serious allergic reactions
- Angioneurotic oedema
- Anaphylaxis
- Long period of observation and treatment required
Use in Special Populations
- No dose adjustment needed in mild renal impairment
- Caution in severe renal impairment
- Not to be used in hepatic impairment
- No effect on ability to drive or use machines
Overdose Effects
- Typical symptoms of overdosage
- Hearing loss
- Severe nausea
- Vomiting
- Diarrhoea
- Gastric lavage and general supportive measures
Storage Conditions
- Keep in dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C38H72N2O12
- Chemical Structure Image URL
Common Questions
- Definition of Odazin 500 mg Tablet
- Uses of Odazin 500 mg Tablet
- Side Effects of Odazin 500 mg Tablet
- Storage and disposal instructions for Odazin 500 mg Tablet
- Potential for causing diarrhea
- Safety of Odazin 500 mg Tablet
- Classification as an antibiotic
- Response if symptoms persist after taking Odazin 500 mg Tablet
- Quick Tips for usage