Romycin 500 mg (Tablet)

Indications

• lower respiratory tract infections
• upper respiratory tract infections
• otitis media
• sinusitis
• pharyngitis
• tonsillitis
• skin infections
• soft tissue infections
• sexually transmitted diseases
• non-gonococcal urethritis
• cervicitis

Pharmacology

• acid-stable
• orally administered
• absorption on empty stomach
• high concentration in phagocytes
• active transport to site of infection
• bacteriostatic levels in infected tissue
• pharmacokinetics - adults
• pharmacokinetics - children
• pharmacokinetics - IV infusion
• tissue concentration
• microbial protein synthesis

Dosage

• 500 mg once daily orally for adults
• 1 gm single dose for adults
• 10 mg/kg body weight for children
• typhoid fever dosage
• IV infusion dosage for pneumonia
• IV infusion dosage for pelvic inflammatory disease

Administration

• reconstitution procedure for suspension
• time of administration in relation to meals

Interaction

• interaction with antacids
• interaction with carbamazepine
• interaction with cyclosporin
• interaction with digoxin
• interaction with ergot derivatives
• interaction with methylprednisolone
• interaction with theophylline
• interaction with warfarin
• interaction with terfenadine

Contraindications

• hypersensitivity to azithromycin
• co-administration with ergot derivatives
• contraindicated in hepatic diseases

Side Effects

• gastrointestinal side effects
• allergic reactions
• elevations in liver transaminases
• cholestatic jaundice
• reductions in neutrofil counts
• hearing impairment

Pregnancy & Lactation

• Pregnancy Category B
• animal reproduction studies
• caution in use during pregnancy
• caution in use during lactation

Precautions & Warnings

• serious allergic reactions
• angioneurotic oedema
• anaphylaxis

Use in Special Populations

• use in renal impairment
• caution in severe renal impairment
• use in hepatic impairment
• effects on ability to drive and use machines

Overdose Effects

• typical symptoms of overdosage
• supportive measures for overdose

Storage Conditions

• storage in dry place
• protection from light and heat
• keep out of reach of children

Chemical Structure

• molecular formula
• chemical structure

Common Questions about Romycin 500 mg Tablet

• action of Romycin
• uses of Romycin
• side effects of Romycin
• storage and disposal instructions
• diarrhea as a side effect
• safety of Romycin
• antibiotic classification
• consultation if no improvement
• quick tips for medication use

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