Rozith 500 mg (Tablet)

Unit Price: ৳ 50.00 (2 x 6: ৳ 600.00)

Strip Price: ৳ 300.00

Medicine Details

Category	Details
Generic	Azithromycin dihydrate
Company	Healthcare pharmaceuticals ltd
Also available as	Rozith 250 mg tablet Rozith 200 mg suspension Rozith 500 mg injection

Title

Rozith 500 mg Tablet

Description

Azithromycin tablet used for various infections such as respiratory, skin, and sexually transmitted diseases in men and women.

DosageForm

Oral
Injection

RecommendedDosage

Adult:
- 500 mg once daily orally for 3 days
- 500 mg once on day 1 then 250 mg once on days 2-5 for 4 days
Children:
- 10 mg/kg body weight once daily for 3 days for child over 6 months
- 200 mg for 3 days if body weight is 15-25 kg
- 300 mg for 3 days if body weight is 26-35 kg
- 400 mg for 3 days if body weight is 36-45 kg

AdministrationInstructions

Azithromycin should be taken at least 1 hour before or 2 hours after a meal.

Pharmacology

Azithromycin is acid-stable, readily absorbed, and acts by binding to the 50S ribosomal subunit of susceptible microorganisms, interfering with microbial protein synthesis.

ModeOfAction

Azithromycin is actively transported to the site of infection and exhibits a prolonged terminal half-life allowing a large single dose to be administered while maintaining bacteriostatic levels in the infected tissue for several days.

Indications

Lower respiratory tract infections
Upper respiratory tract infections
Otitis media
Skin and soft tissue infections
Non-gonococcal urethritis
Cervicitis due to Chlamydia trachomatis

Contraindications

Hypersensitivity to Azithromycin or any other macrolide antibiotic
Co-administration of ergot derivatives
Hepatic diseases

SideEffects

Gastrointestinal discomfort
Allergic reactions
Elevations in liver transaminases
Rare occurrences of cholestatic jaundice
Transient mild reductions in neutrophil counts
Reversible hearing impairment in some patients

PregnancyAndLactation

PregnancyCategory: B
Recommendation: Use during pregnancy only if adequate alternatives are not available, caution during lactation

PrecautionsAndWarnings

Rare serious allergic reactions have been reported. Caution in patients with renal or hepatic impairment.

OverdoseEffects

Typical symptoms include hearing loss, severe nausea, vomiting, and diarrhea. Gastric lavage and general supportive measures are indicated.

StorageConditions

Keep in a dry place, away from light and heat. Keep out of the reach of children.

ChemicalStructure

MolecularFormula: C38H72N2O12
ChemicalStructureImage: https://medex.com.bd/storage/res/g-res-100-azithromycin-dihydrate-chemical-structure-tFo4BQqfsRzQwcODCGo2.svg

Interactions

Antacid
Carbamazepine
Cyclosporin
Digoxin
Ergot derivatives
Methylprednisolone
Theophylline
Warfarin
Terfenadine

PediatricUses

RenalImpairment: No dose adjustment needed in patients with mild renal impairment, caution in severe impairment
HepaticImpairment: Not recommended due to hepatic excretion pathway
EffectsOnAbilityToDrive: No evidence of effect on ability to drive or operate machinery

CommonQuestions

WhatIsRozith: Rozith 500 mg Tablet prevents the synthesis of essential proteins required by bacteria to carry out vital functions.
Uses: Treatment and prevention of community-acquired pneumonia, pharyngitis/tonsillitis, and skin and soft tissue infections.
SideEffects:
- Diarrhea
- Dry or scaly skin
- Abdominal pain
- Difficult or painful urination
- Vomiting
- Fever
- Acid or sour stomach
- Aggression or anger
- Excessive air or gas in the stomach
- Heartburn
StorageAndDisposal: Keep in a cool dry place and its original packaging, ensuring it remains unreachable to children and pets.
CauseOfDiarrhea: Yes, it can cause diarrhea due to its impact on helpful bacteria in the stomach or intestine.
Safety: It is safe if used at prescribed doses as advised by a doctor.
Classification: Rozith 500 mg Tablet belongs to a class of antibiotics known as macrolides.