Thiza 200 mg/5 ml (Powder for Suspension)

15 ml bottle: ৳ 85.00

Medicine Details

Category Details
Generic Azithromycin dihydrate
Company Kumudini pharma ltd
Also available as
Thiza 500 mg tablet

Indications

  • Lower respiratory tract infections treatment
  • Upper respiratory tract infections treatment
  • Skin and soft tissue infections treatment
  • Sexually transmitted diseases treatment

Pharmacology

  • Acid-stable for oral consumption
  • High absorption on an empty stomach
  • Time to peak concentration in adults
  • High concentration in phagocytes
  • Release of large concentrations of azithromycin during active phagocytosis
  • Over 50 times higher concentration in tissues than plasma
  • Biliary excretion as a major elimination route

Dosage

  • 500 mg once daily orally for 3 days in adults
  • 500 mg once on day 1, then 250 mg once on days 2-5 for 4 days in adults
  • 1 gm single dose for sexually transmitted diseases in adults
  • Dose adjustment for children based on body weight

Administration

  • Reconstitution procedure for suspension
  • Intake 1 hour before or 2 hours after a meal

Interaction

  • Interaction with antacids
  • Interaction with carbamazepine
  • Potential interference with the metabolism of cyclosporin
  • Impairment of digoxin metabolism
  • Do not co-administer with ergot derivatives
  • Negligible effect on methylprednisolone pharmacokinetics

Contraindications

  • Hypersensitivity to azithromycin or macrolide antibiotics
  • Co-administration with ergot derivatives
  • Patients with hepatic diseases

Side Effects

  • Mild to moderate gastrointestinal side-effects
  • Allergic reactions such as rash or photosensitivity
  • Rare reports of serious hypersensitivity reactions
  • Reversible elevations in liver transaminases
  • Cholestatic jaundice
  • Transient mild reductions in neutrophil counts
  • Reversible hearing impairment with higher doses

Pregnancy & Lactation

  • Pregnancy Category B
  • No evidence of harm to the fetus in animal studies
  • Caution in use during pregnancy if alternatives are not available
  • Unknown secretion in breast milk
  • Caution when administered to nursing women

Precautions & Warnings

  • Rare serious allergic reactions reported
  • Reported cases of angioneurotic edema and anaphylaxis

Use in Special Populations

  • No dose adjustment needed in mild renal impairment
  • Caution in severe renal impairment
  • Avoid use in patients with hepatic impairment
  • No effect on driving or use of machines

Overdose Effects

  • Typical symptoms of macrolide antibiotic overdosage
  • Supportive measures indicated

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C38H72N2O12
  • Chemical Structure Image URL

Common Questions about Thiza 200 mg/5 ml Suspension

  • Information about Thiza 200 mg/5 ml Syrup
  • Uses of Thiza 200 mg/5 ml Syrup
  • List of side effects of Thiza 200 mg/5 ml Syrup
  • Instructions for storage and disposal of Thiza 200 mg/5 ml Syrup
  • Potential side effect of diarrhea
  • Safety of Thiza 200 mg/5 ml Syrup
  • Categorization as an antibiotic
  • Guidance if symptoms persist
  • Quick tips for usage

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