Thromax 500 mg (Tablet)

Indications

• Lower respiratory tract infections
• Upper respiratory tract infections
• Otitis media
• Skin and soft tissue infections
• Sexually transmitted diseases

Mode of Action

• Readily absorbed orally
• Time to peak concentration
• High concentration in phagocytes
• Binding to 50S ribosomal subunit
• Interfering with microbial protein synthesis
• High lipid solubility

Dosage

• 500 mg once daily orally for 3 days
• 1 gm single dose for sexually transmitted diseases
• 10 mg/kg body weight for children over 6 months
• Azithromycin Injection for adult patients with community-acquired pneumonia and pelvic inflammatory disease

Administration

• Oral administration
• Reconstitution procedure for suspension
• Timing of intake in relation to meals

Interaction

• Interaction with antacids
• Potential interference with carbamazepine, cyclosporine, digoxin, ergot derivatives, methylprednisolone, theophylline, warfarin, terfenadine

Contraindications

• Hypersensitivity to Azithromycin or macrolide antibiotics
• Co-administration with ergot derivatives
• Patients with hepatic diseases

Side Effects

• Gastrointestinal side effects
• Allergic reactions
• Reversible elevations in liver transaminases
• Rare cases of cholestatic jaundice
• Transient mild reductions in neutrophil counts
• Reversible hearing impairment

Pregnancy & Lactation

• Pregnancy Category B
• No evidence of harm to fetus in animal studies
• Caution in use during pregnancy and lactation
• Unknown secretion in breast milk

Precautions & Warnings

• Rare serious allergic reactions
• Reports of recurrent symptoms and long observation periods

Use in Special Populations

• No dose adjustment in mild renal impairment
• Caution in severe renal impairment
• Not to be used in patients with hepatic disease
• No effect on ability to drive or operate machinery

Overdose Effects

• Typical symptoms of overdose with macrolide antibiotics
• Indications for gastric lavage and general supportive measures

Storage Conditions

• Dry place away from light and heat
• Keep out of the reach of children

Chemical Structure

• Molecular Formula: C38H72N2O12
• Chemical Structure Image Link

Common Questions

• Thromax 500 mg Tablet action
• Uses of Thromax 500 mg Tablet
• Side effects of Thromax 500 mg Tablet
• Storage and disposal instructions
• Diarrhea as a side effect
• Safety of Thromax 500 mg Tablet
• Classification as an antibiotic
• Guidance if no improvement noticed after 3 days of intake
• Quick tips for usage

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