Virzith 200 mg/5 ml (Powder for Suspension)

20 ml bottle: ৳ 100.00

Medicine Details

Title

  • Virzith 200 mg/5 ml Syrup

Categories

  • Medicine
  • Health
  • Pharmacology

Description

  • Azithromycin oral suspension for treating infections in the respiratory tract, sexually transmitted diseases, and skin and soft tissue infections. Details dosage, pharmacology, administration, interactions, contraindications, side effects, pregnancy and lactation considerations, precautions, overdose effects, storage conditions, and chemical structure.

Indication

  • Lower respiratory tract infections
  • Bronchitis
  • Pneumonia
  • Upper respiratory tract infections
  • Sinusitis
  • Pharyngitis
  • Tonsillitis
  • Otitis media
  • Skin and soft tissue infections
  • Non-gonococcal urethritis
  • Cervicitis

Pharmacology

  • Administration on empty stomach
  • Readily absorbed
  • High concentration in phagocytes
  • Active transport to infection sites
  • Long half-life for bacteriostatic effect
  • Binding to 50S ribosomal subunit of microorganisms
  • In vitro and clinical activity against various microorganisms

Dosage

  • 500 mg once daily for 3 days (adult)
  • 500 mg once on day 1, then 250 mg once daily for 4 days (adult)
  • 10 mg/kg body weight once daily for 3 days in children over 6 months
  • Azithromycin injection for intravenous use

Administration

  • Oral suspension reconstitution procedure
  • Administration 1 hour before or 2 hours after meal

Interaction

  • Interaction with antacids
  • Potential interference with carbamazepine, cyclosporin, digoxin, ergot derivatives, methylprednisolone, theophylline, warfarin, terfenadine

Contraindications

  • Hypersensitivity to Azithromycin or macrolide antibiotics
  • Co-administration with ergot derivatives
  • Hepatic diseases

Side effects

  • Gastrointestinal side effects
  • Allergic reactions
  • Reversible liver transaminase elevations
  • Rare cases of cholestatic jaundice
  • Transient mild reductions in neutrophil counts
  • Reversible hearing impairment in prolonged use

Pregnancy and lactation

  • Pregnancy Category B
  • No evidence of harm in animal studies
  • Caution in use during pregnancy and lactation without adequate alternatives

Precautions and warnings

  • Rare serious allergic reactions reported
  • Persistent symptoms may require long-term observation and treatment

Use in special populations

  • No dose adjustment in mild renal impairment
  • Caution in severe renal impairment
  • Not to be used in hepatic impairment
  • No effect on driving or operating machinery

Overdose effects

  • Typical symptoms include hearing loss, severe nausea, vomiting, and diarrhea
  • General supportive measures and gastric lavage indicated

Storage conditions

  • Keep in dry place away from light and heat
  • Keep out of reach of children

Chemical structure

  • Molecular Formula - C38H72N2O12
  • Chemical Structure - (Image: Chemical Structure of Azithromycin Dihydrate)

Commonly asked questions

  • What is Virzith 200 mg/5 ml Syrup?
  • Uses of Virzith 200 mg/5 ml Syrup
  • Side effects of Virzith 200 mg/5 ml Syrup
  • Storage and disposal instructions for Virzith 200 mg/5 ml Syrup
  • Possible diarrhea side effect
  • Safety of Virzith 200 mg/5 ml Syrup
  • Virzith 200 mg/5 ml Syrup as an antibiotic
  • Instructions if symptoms do not improve
  • Quick Tips for usage

Other attributes

  • Reversible absorption on empty stomach
  • Pharmacokinetic interaction with antacids
  • No significant effect on plasma levels of carbamazepine
  • Cautions for co-administration with cyclosporin
  • Reported impairment of digoxin metabolism
  • Theoretical possibility of ergotism
  • No significant effect on methylprednisolone pharmacokinetics
  • No evidence of theophylline interaction
  • No alteration of warfarin's anticoagulant effect
  • No effect on terfenadine pharmacokinetics

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