Zinex 250 mg (Tablet)
Unit Price: ৳ 20.06 (2 x 6: ৳ 240.72)
Strip Price: ৳ 120.36
Medicine Details
Category | Details |
---|---|
Generic | Azithromycin dihydrate |
Company | Alco pharma ltd |
Also available as |
Indications
- Lower respiratory tract infections treatment
- Upper respiratory tract infections treatment
- Otitis media treatment
- Skin and soft tissue infections treatment
- Treatment of bronchitis
- Treatment of pneumonia
- Treatment of sinusitis
- Treatment of pharyngitis
- Treatment of tonsillitis
- Treatment of non-gonococcal urethritis
- Treatment of cervicitis
- Treatment of Chlamydia trachomatis infections
Pharmacology
- Oral administration
- Absorption on empty stomach
- Targeted phagocyte concentration
- High lipid solubility
- Bacteriostatic levels maintenance
- Half-life of 68 hours
- Polyphasic plasma concentration decline
- Biliary excretion route of elimination
- Active against gram-positive microorganisms
- Active against gram-negative microorganisms
- Active against Chlamydia pneumoniae
- Ribosomal subunit binding mechanism
- Interference with microbial protein synthesis
Dosage
- Oral administration for adults and children
- Different dosage regimens based on age and weight
- Single and multiple day dosing
- Intravenous infusion dosage for adults
- Community-acquired pneumonia treatment dosage regimens
- Pelvic inflammatory disease treatment dosage regimens
- No established safety for children under 16 years
Administration
- Suspension reconstitution procedure
- Shaking the bottle to loosen powder
- Adding boiled and cooled water
- Shaking until powder is mixed with water
- Timing of intake 1 hour before or 2 hours after meal
Interaction
- Antacid interaction precautions
- Carbamazepine interaction precautions
- Cyclosporin interaction precautions
- Digoxin interaction precautions
- Ergot derivatives interaction precautions
- Methylprednisolone interaction precautions
- Theophylline interaction precautions
- Warfarin interaction precautions
- Terfenadine interaction precautions
Contraindications
- Hypersensitivity to Azithromycin
- Contraindicated with ergot derivatives
- Contraindicated in patients with hepatic diseases
Side Effects
- Low incidence of side effects
- Gastrointestinal side effects
- Allergic reactions
- Reversible elevations in liver transaminases
- Cholestatic jaundice cases
- Transient mild reductions in neutrophil counts
- Reversible hearing impairment in some patients
Pregnancy & Lactation
- Pregnancy Category B
- No harm to fetus demonstrated in animal studies
- Caution in use during pregnancy
- Unknown secretion in breast milk
- Caution in use during lactation
Precautions & Warnings
- Rare serious allergic reactions reported
- Reports of angioneurotic edema and anaphylaxis
- Recurrent symptoms observed
- Long period of observation and treatment required
Use in Special Populations
- No dose adjustment in mild renal impairment
- Caution in more severe renal impairment
- Hepatic impairment avoidance
- Effects on ability to drive and use machines
Overdose Effects
- No data on Zinex overdosage
- Typical macrolide antibiotic overdose symptoms
- Gastric lavage and supportive measures indicated
Storage Conditions
- Dry and cool storage
- Protection from light and heat
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C38H72N2O12
- Chemical Structure Image provided
Common Questions
- Action mechanism of Zinex 250 mg Tablet
- Uses of Zinex 250 mg Tablet
- Specific side effects of Zinex 250 mg Tablet
- Storage and disposal instructions
- Diarrhea as a side effect
- Safety of Zinex 250 mg Tablet
- Antibiotic classification of Zinex 250 mg Tablet
- When to consult the doctor if symptoms persist
- Quick Tips for Zinex 250 mg Tablet usage