Zinex 250 mg (Tablet)

Unit Price: ৳ 20.06 (2 x 6: ৳ 240.72)
Strip Price: ৳ 120.36

Medicine Details

Indications

  • Lower respiratory tract infections treatment
  • Upper respiratory tract infections treatment
  • Otitis media treatment
  • Skin and soft tissue infections treatment
  • Treatment of bronchitis
  • Treatment of pneumonia
  • Treatment of sinusitis
  • Treatment of pharyngitis
  • Treatment of tonsillitis
  • Treatment of non-gonococcal urethritis
  • Treatment of cervicitis
  • Treatment of Chlamydia trachomatis infections

Pharmacology

  • Oral administration
  • Absorption on empty stomach
  • Targeted phagocyte concentration
  • High lipid solubility
  • Bacteriostatic levels maintenance
  • Half-life of 68 hours
  • Polyphasic plasma concentration decline
  • Biliary excretion route of elimination
  • Active against gram-positive microorganisms
  • Active against gram-negative microorganisms
  • Active against Chlamydia pneumoniae
  • Ribosomal subunit binding mechanism
  • Interference with microbial protein synthesis

Dosage

  • Oral administration for adults and children
  • Different dosage regimens based on age and weight
  • Single and multiple day dosing
  • Intravenous infusion dosage for adults
  • Community-acquired pneumonia treatment dosage regimens
  • Pelvic inflammatory disease treatment dosage regimens
  • No established safety for children under 16 years

Administration

  • Suspension reconstitution procedure
  • Shaking the bottle to loosen powder
  • Adding boiled and cooled water
  • Shaking until powder is mixed with water
  • Timing of intake 1 hour before or 2 hours after meal

Interaction

  • Antacid interaction precautions
  • Carbamazepine interaction precautions
  • Cyclosporin interaction precautions
  • Digoxin interaction precautions
  • Ergot derivatives interaction precautions
  • Methylprednisolone interaction precautions
  • Theophylline interaction precautions
  • Warfarin interaction precautions
  • Terfenadine interaction precautions

Contraindications

  • Hypersensitivity to Azithromycin
  • Contraindicated with ergot derivatives
  • Contraindicated in patients with hepatic diseases

Side Effects

  • Low incidence of side effects
  • Gastrointestinal side effects
  • Allergic reactions
  • Reversible elevations in liver transaminases
  • Cholestatic jaundice cases
  • Transient mild reductions in neutrophil counts
  • Reversible hearing impairment in some patients

Pregnancy & Lactation

  • Pregnancy Category B
  • No harm to fetus demonstrated in animal studies
  • Caution in use during pregnancy
  • Unknown secretion in breast milk
  • Caution in use during lactation

Precautions & Warnings

  • Rare serious allergic reactions reported
  • Reports of angioneurotic edema and anaphylaxis
  • Recurrent symptoms observed
  • Long period of observation and treatment required

Use in Special Populations

  • No dose adjustment in mild renal impairment
  • Caution in more severe renal impairment
  • Hepatic impairment avoidance
  • Effects on ability to drive and use machines

Overdose Effects

  • No data on Zinex overdosage
  • Typical macrolide antibiotic overdose symptoms
  • Gastric lavage and supportive measures indicated

Storage Conditions

  • Dry and cool storage
  • Protection from light and heat
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C38H72N2O12
  • Chemical Structure Image provided

Common Questions

  • Action mechanism of Zinex 250 mg Tablet
  • Uses of Zinex 250 mg Tablet
  • Specific side effects of Zinex 250 mg Tablet
  • Storage and disposal instructions
  • Diarrhea as a side effect
  • Safety of Zinex 250 mg Tablet
  • Antibiotic classification of Zinex 250 mg Tablet
  • When to consult the doctor if symptoms persist
  • Quick Tips for Zinex 250 mg Tablet usage

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