Zithracin 500 mg (Tablet)

Unit Price: ৳ 35.00 (6's pack: ৳ 210.00)

Medicine Details

Indications

  • Lower respiratory tract infections
  • Upper respiratory tract infections
  • Otitis media
  • Skin and soft tissue infections
  • Sexually transmitted diseases

Pharmacology

  • Acid-stable
  • Readily absorbed
  • High concentration in phagocytes
  • Active transport to site of infection
  • Bacteriostatic levels in infected tissue
  • Binding to 50S ribosomal subunit
  • Interfering with microbial protein synthesis
  • Active against various microorganisms

Dosage

  • 500 mg once daily orally for adults
  • Dose by body weight for children
  • Dosage for intravenous (IV) infusion in adults
  • Dosage for pelvic inflammatory disease in adults
  • No established dosage for children or adolescents under 16 years

Administration

  • Reconstitution procedure for suspension
  • Should be taken at least 1 hour before or 2 hours after meal

Interaction

  • Interaction with antacids
  • Potential interactions with carbamazepine, cyclosporin, digoxin, ergot derivatives, methylprednisolone, theophylline, warfarin, terfenadine

Contraindications

  • Hypersensitivity to azithromycin or macrolide antibiotics
  • Co-administration with ergot derivatives
  • Hepatic diseases

Side Effects

  • Gastrointestinal side effects
  • Allergic reactions
  • Elevations in liver transaminases
  • Cholestatic jaundice
  • Transient reductions in neutrophil counts
  • Reversible hearing impairment

Pregnancy & Lactation

  • Pregnancy category B
  • No evidence of harm to fetus from animal studies
  • Caution in use during breastfeeding

Precautions & Warnings

  • Rare serious allergic reactions reported
  • Caution in renal impairment
  • Avoid use in hepatic impairment
  • No evidence of impact on ability to drive or use machines

Use in Special Populations

  • No dose adjustment needed in mild renal impairment
  • Caution in use for patients with severe renal impairment
  • Not for use in patients with hepatic disease
  • No impact on ability to drive or use machinery

Overdose Effects

  • Typical symptoms of macrolide antibiotic overdosage
  • Supportive measures indicated

Storage Conditions

  • Keep in dry place away from light and heat
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C38H72N2O12
  • Chemical Structure Image

Common Questions about Zithracin 500 mg Tablet

  • Action mechanism of Zithracin 500 mg Tablet
  • Uses of Zithracin 500 mg Tablet
  • List of side effects
  • Storage and disposal instructions
  • Possibility of diarrhea as a side effect
  • Safety of Zithracin 500 mg Tablet
  • Classification as an antibiotic
  • Need for medical advice if no improvement
  • Quick tips for usage

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