Zithrin 500 mg/vial (IV Infusion)
500 mg vial: ৳ 460.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Azithromycin dihydrate |
| Company | Renata limited |
| Also available as |
Title
Zithrin 500 mg/vial Injection
Categories
- Antibiotic
- Macrolide Antibiotic
- Infection Treatment
- Oral Suspension
- IV Infusion
Indications
- Lower respiratory tract infections
- Upper respiratory tract infections
- Otitis media
- Skin and soft tissue infections
- Non-gonococcal urethritis
- Cervicitis due to Chlamydia trachomatis
Pharmacology
- Orally administered
- Readily absorbed
- Time to peak concentration
- High concentration in phagocytes
- Transport to site of infection
- Biliary excretion
- Microbial protein synthesis interference
Dosage
- 500 mg once daily for 3 days (Adult oral)
- 1 gm as a single dose or 500 mg once followed by 250 mg for 2 days (Chlamydia trachomatis)
- 10 mg/kg body weight for 3 days for children over 6 months
- 500 mg for typhoid fever
- 500 mg as a single daily IV dose for community-acquired pneumonia
Administration
- Oral administration
- Reconstitution procedure for suspension
- Take at least 1 hour before or 2 hours after meal
Interaction
- Antacid co-administration
- Carbamazepine interaction
- Cyclosporin interference
- Pharmacokinetic interaction with digoxin
- Avoid co-administration with ergot derivatives
- No significant effect on methylprednisolone metabolism
- No evidence of theophylline interaction
- Co-administration with warfarin
Contraindications
- Hypersensitivity to Azithromycin
- Co-administration with ergot derivatives
- Patients with hepatic diseases
Side Effects
- Gastrointestinal symptoms
- Allergic reactions
- Reversible liver transaminase elevations
- Rare cholestatic jaundice
- Mild neutrofil count reductions
- Rare reversible hearing impairment
Pregnancy & Lactation
- Pregnancy Category B
- No evidence of harm to fetus in animal studies
- Caution in pregnant and nursing women
Precautions & Warnings
- Rare serious allergic reactions
- Recurrence of symptoms requiring long-term observation and treatment
Use in Special Populations
- No dose adjustment in mild renal impairment
- Caution in severe renal impairment
- Avoid use in hepatic impairment
- No effect on ability to drive or operate machines
Overdose Effects
- Typical symptoms include hearing loss, severe nausea, vomiting, and diarrhea
- Gastric lavage and general supportive measures indicated
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C38H72N2O12
- Chemical Structure Image URL
Common Questions
- What is Zithrin 500 mg/vial IV Infusion?
- Uses of Zithrin 500 mg/vial IV Infusion
- Side Effects of Zithrin 500 mg/vial IV Infusion
- Storage and disposal instructions
- Possibility of diarrhea
- Safety
- Antibiotic class
- Seek medical help if symptoms persist or worsen
- Quick Tips