Zithrolex 500 mg (Tablet)
Unit Price: ৳ 28.00 (6's pack: ৳ 168.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Azithromycin dihydrate |
| Company | Mystic pharmaceuticals ltd |
Title
- Zithrolex 500 mg Tablet
Categories
- Antibiotic
- Medication
- Pharmaceutical
Indications
- Lower respiratory tract infections
- Upper respiratory tract infections
- Sinusitis
- Pharyngitis/Tonsillitis
- Otitis media
- Skin and soft tissue infections
- Sexually transmitted diseases in men and women
- Non-gonococcal urethritis
- Cervicitis
- Chlamydia trachomatis
Mode of Action
- Acid-stable
- Oral administration
- Readily absorbed
- Peak concentration
- High concentration in phagocytes
- Active transportation to site of infection
- High tissue concentration
- Bacteriostatic levels maintenance
- Binding to 50S ribosomal subunit
- Interference with microbial protein synthesis
- Ion trapping
- High lipid solubility
- Microbiological activity against isolates
- In vitro and clinical effectiveness
Dosage
- 500 mg once daily orally for 3 days for adults
- 1 gm single dose for sexually transmitted diseases caused by Chlamydia trachomatis in adults
- Variable dose for children based on body weight
- Azithromycin injection for IV infusion only with recommended doses for specific conditions
Administration
- Reconstitution procedure for suspension
- Timing in relation to meals
Interaction
- Antacid interaction
- Carbamazepine interaction
- Cyclosporin interaction
- Digoxin interaction
- Ergot derivatives interaction
- Methylprednisolone interaction
- Theophylline interaction
- Warfarin interaction
- Terfenadine interaction
Contraindications
- Hypersensitivity to Azithromycin or macrolide antibiotics
- Co-administration with ergot derivatives
- Hepatic diseases
Side Effects
- Gastrointestinal side-effects
- Nausea
- Abdominal discomfort
- Vomiting
- Flatulence
- Diarrhoea
- Allergic reactions
- Rash
- Photosensitivity
- Reversible elevations in liver transaminases
- Cholestatic jaundice
- Reductions in neutrophil counts
- Hearing impairment
Pregnancy & Lactation
- Pregnancy Category B
- Animal reproduction studies demonstrating no harm to fetus
- Lack of adequate and well-controlled studies in pregnant women
- Caution in administration to nursing women
Precautions & Warnings
- Rare serious allergic reactions
- Angioneurotic oedema
- Anaphylaxis
Use in Special Populations
- Use in renal impairment
- Use in hepatic impairment
- Effects on ability to drive and use machines
Overdose Effects
- Typical symptoms of macrolide antibiotic overdosage
- Gastric lavage and general supportive measures
Storage Conditions
- Dry place away from light and heat
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C38H72N2O12
Commonly Asked Questions
- Definition and mechanism of action
- Uses of Zithrolex 500 mg Tablet
- Side effects
- Storage and disposal instructions
- Possibility of diarrhea
- Safety
- Antibiotic classification
- Assessment of treatment effectiveness
- Quick tips for usage
Images
- Chemical structure image
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