Zitrex 200 mg/5 ml (Powder for Suspension)

Indications

• Lower respiratory tract infections treatment
• Upper respiratory tract infections treatment
• Otitis media treatment
• Skin and soft tissue infections treatment
• Non-gonococcal urethritis treatment
• Cervicitis treatment

Pharmacology

• Oral administration
• Absorption on an empty stomach
• Time to peak concentration
• High concentration in phagocytes
• Transport to infection site
• Release during active phagocytosis
• Higher tissue concentrations
• Ion trapping
• High lipid solubility
• Large single dose administration
• Long bacteriostatic levels maintenance
• Plasma concentration decline pattern
• Mean apparent plasma clearance
• Terminal elimination half-life
• Biliary excretion route
• Unchanged drug elimination in urine
• Microbial protein synthesis interference
• Nucleic acid synthesis unaffected
• Activity against various microorganisms

Dosage

• Adult oral dosage
• Adult sexually transmitted diseases dosage
• Children's dosage
• Azithromycin injection dosage for adults
• Safety in children/adolecents under 16 years

Administration

• Suspension reconstitution procedure
• Timing in relation to meals

Interaction

• Antacid interaction
• Carbamazepine interaction
• Cyclosporin interaction
• Digoxin interaction
• Ergot derivatives interaction
• Methylprednisolone interaction
• Theophylline interaction
• Warfarin interaction
• Terfenadine interaction

Contraindications

• Hypersensitivity to Azithromycin
• Hypersensitivity to macrolide antibiotics
• Co-administration with ergot derivatives
• Hepatic diseases

Side Effects

• Low incidence of side effects
• Majority gastrointestinal in origin
• Allergic reactions
• Liver transaminases elevations
• Cholestatic jaundice
• Neutrophil count reductions
• Reversible hearing impairment

Pregnancy & Lactation

• Pregnancy category B
• Animal reproduction studies
• Use during pregnancy caution
• Secretion in breast milk caution

Precautions & Warnings

• Serious allergic reactions
• Reporting recurrent symptoms
• Use in renal impairment
• Use in hepatic impairment
• No effect on ability to drive/machines

Use in Special Populations

• No dose adjustment for mild renal impairment
• Caution in more severe renal impairment
• Avoid in hepatic disease
• No effect on ability to drive/machines

Overdose Effects

• Typical symptoms of macrolide overdosage
• Gastric lavage and supportive measures

Storage Conditions

• Dry place away from light and heat
• Keep out of the reach of children

Chemical Structure

• Molecular formula
• Chemical structure image

Common Questions about Zitrex 200 mg/5 ml Suspension

• Action of Zitrex 200 mg/5 ml Syrup
• Uses of Zitrex 200 mg/5 ml Syrup
• Side effects of Zitrex 200 mg/5 ml Syrup
• Storage and disposal instructions for Zitrex 200 mg/5 ml Syrup
• Diarrhea as a side effect
• Safety of Zitrex 200 mg/5 ml Syrup
• Zitrex 200 mg/5 ml Syrup as an antibiotic
• Instructions for non-improvement after taking Zitrex 200 mg/5 ml Syrup
• Quick Tips

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