Zycin 500 mg (Tablet)
Unit Price: ৳ 35.00 (2 x 6: ৳ 420.00)
Strip Price: ৳ 210.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Azithromycin dihydrate |
| Company | Globe pharmaceuticals ltd |
| Also available as |
Indications
- Lower respiratory tract infections treatment
- Upper respiratory tract infections treatment
- Skin and soft tissue infections treatment
- Sexually transmitted diseases treatment
- Treatment of non-gonococcal urethritis
- Treatment of cervicitis due to Chlamydia trachomatis
Pharmacology
- Oral administration with no need for protection from gastric acids
- Readily absorbed
- Greater absorption on an empty stomach
- Time to peak concentration
- High concentration in phagocytes
- Active transport to the site of infection
- Polyphasic decline in plasma concentrations
- Terminal elimination half-life
- Biliary excretion as a major route of elimination
- Microbial protein synthesis interference
Dosage
- 500 mg once daily orally for 3 days in adults
- 500 mg once on day 1, then 250 mg once on days 2-5 for 4 days in adults
- 1 gm given as a single dose or 500 mg once on day 1, followed by 250 mg once daily for next 2 days in adults
- 10 mg/kg body weight once daily for 3 days for child over 6 months
- Azithromycin injection for IV infusion in adults
Administration
- Reconstitution procedure of suspension
- Shaking the bottle well
- Adding boiled and cooled water
- Shaking until powder is completely mixed with water
- Taking at least 1 hour before or 2 hours after meal
Interaction
- Interaction with antacid
- Interaction with carbamazepine
- Interaction with cyclosporin
- Interaction with digoxin
- Interaction with ergot derivatives
- Interaction with methylprednisolone
- Interaction with theophylline
- Interaction with warfarin
- Interaction with terfenadine
Contraindications
- Hypersensitivity to Azithromycin or macrolide antibiotics
- Co-administration of ergot derivatives
- Presence of hepatic diseases
Side Effects
- Gastrointestinal side-effects
- Allergic reactions
- Rare reports of serious hypersensitivity reactions
- Reversible elevations in liver transaminases
- Rare cases of cholestatic jaundice
- Transient mild reductions in neutrophil counts
- Reversible hearing impairment in some patients
Pregnancy & Lactation
- Pregnancy Category B
- Animal reproduction studies evidence
- No adequate and well controlled studies in pregnant women
- Caution in use during pregnancy
- Unknown secretion in breast milk
- Caution in use during lactation
Precautions & Warnings
- Rare serious allergic reactions reported
- Caution in use in renal impairment
- Caution in use in hepatic impairment
- No evidence of effect on ability to drive or use machines
Overdose Effects
- Typical symptoms of overdosage with macrolide antibiotics
- Hearing loss
- Severe nausea, vomiting, and diarrhea
- Recommended supportive measures
Storage Conditions
- Dry place away from light and heat
- Out of the reach of children
Chemical Structure
- Molecular Formula: C38H72N2O12
Common Questions
- Action of Zycin 500 mg Tablet
- Uses of Zycin 500 mg Tablet
- Side Effects of Zycin 500 mg Tablet
- Storage and disposal instructions for Zycin 500 mg Tablet
- Possibility of diarrhea with Zycin 500 mg Tablet
- Safety of Zycin 500 mg Tablet
- Classification of Zycin 500 mg Tablet as an antibiotic
- Recommendations if no improvement is noticed
- Quick Tips for Zycin 500 mg Tablet