Claricin 500 mg (Tablet)
Unit Price: ৳ 45.00 (2 x 4: ৳ 360.00)
Strip Price: ৳ 180.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clarithromycin |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Acute bacterial exacerbation of chronic bronchitis in adults
- Acute maxillary sinusitis
- Community-acquired pneumonia
- Pharyngitis or tonsillitis
- Uncomplicated skin and skin structure infections
- Acute otitis media in pediatric patients
- Treatment and prophylaxis of disseminated mycobacterial infections
- Helicobacter pylori infection and duodenal ulcer disease in adults
Pharmacology
- Inhibits microsomal protein synthesis
- Binds to the donor site on the 50S subunit of the bacterial ribosome
- Prevents translocation to the donor site
- Active against most Gram-positive bacteria and Chlamydia
- Better acid stability than Erythromycin
Dosage & Administration
- Different dosing regimens for various conditions and patient groups
- Combination dosing regimens for H. pylori infection
- Specific dosages for adults and pediatric patients
- Guidelines for renal and hepatic impairment
Interaction
- Contraindicated with specific medications like HMG-CoA reductase inhibitors
- Not recommended with certain antiarrhythmics
Contraindications
- Known hypersensitivity to clarithromycin or any macrolide antibacterial drugs
- History of cholestatic jaundice or hepatic dysfunction associated with prior use of clarithromycin
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Stomatitis
- Glossitis
- Headache
- Allergic reactions
- Taste perversion
- Transient central nervous system side effects
Pregnancy & Lactation
- Not recommended during pregnancy
- Caution advised while breastfeeding
Precautions & Warnings
- Discontinue if severe acute hypersensitivity reactions occur
- Avoid in patients with known QT prolongation or receiving drugs known to prolong the QT interval
- Increased risk of all-cause mortality in patients with coronary artery disease
Use in Special Populations
- Established safety and effectiveness for pediatric patients with specific conditions
- Caution advised for pediatric patients under certain age groups
Overdose Effects
- Ingestion of large amounts can lead to gastrointestinal symptoms
- Adverse reactions accompanying overdosage should be treated by prompt elimination of unabsorbed drug and supportive measures
Therapeutic Class
- Macrolides
Storage Conditions
- Keep in a cool and dry place
- Protected from light and moisture
- Reconstituted suspension must be used within specific timeframes
- Keep out of reach of children