Clarocin 500 mg (Tablet)
Unit Price: ৳ 30.00 (2 x 6: ৳ 360.00)
Strip Price: ৳ 180.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clarithromycin |
| Company | Desh pharmaceuticals ltd |
Indications
- Treatment of acute bacterial exacerbation of chronic bronchitis in adults
- Treatment of acute maxillary sinusitis
- Treatment of community-acquired pneumonia
- Treatment of pharyngitis or tonsillitis
- Treatment of uncomplicated skin and skin structure infections
- Treatment of acute otitis media in pediatric patients
- Treatment and prophylaxis of disseminated mycobacterial infections
- Treatment of Helicobacter pylori infection and duodenal ulcer disease in adults
Pharmacology
- Inhibits microsomal protein synthesis in susceptible organisms
- Binds to the donor site on the 50S subunit of the bacterial ribosome
- Active against most Gram-positive bacteria and Chlamydia
- Activity greater than that of Erythromycin against H. Influenzae
- More acid-stable than Erythromycin
- Inactive against most species of Gram-negative bacteria
Dosage & Administration
- Adult dosage for different conditions
- Combination dosing regimens for H. pylori infection
- Pediatric dosage for specific infections
- Administration in renal and hepatic impairment
Interaction
- Contraindicated with specific medications such as HMG-CoA reductase inhibitors and antipsychotics
Contraindications
- Contraindicated in patients with known hypersensitivity to clarithromycin
- Contraindicated in patients with a history of cholestatic jaundice or hepatic dysfunction associated with prior use of clarithromycin
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Stomatitis
- Glossitis
- Headache
- Allergic reactions
- Taste perversion
- Transient central nervous system side effects
Pregnancy & Lactation
- Usage in neonates and children
- Precautions for breastfeeding mothers
Precautions & Warnings
- Discontinue in case of severe acute hypersensitivity reactions
- Avoid in patients with known QT prolongation or receiving drugs known to prolong the QT interval
- Increased risk of all-cause mortality in patients with coronary artery disease
Use in Special Populations
- Safety and effectiveness in pediatric patients
- Use in children 6 months and older
- Use in preventing disseminated Mycobacterium avium complex (MAC) disease
- Safety of Clarithromycin in MAC patients under the age of 20 months
Overdose Effects
- Expected gastrointestinal symptoms with large ingestion
- Supportive measures for adverse reactions accompanying overdosage
Therapeutic Class
- Macrolides
Storage Conditions
- Store in a cool and dry place
- Reconstituted suspension usage within specified timeframes
- Keep out of reach of children