Klabid ER 500 mg (Tablet (Extended Release))
Unit Price: ৳ 74.00 (1 x 7: ৳ 518.00)
Strip Price: ৳ 518.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clarithromycin |
| Company | Unimed unihealth pharmaceuticals ltd |
| Also available as |
Indications
- Acute bacterial exacerbation of chronic bronchitis in adults
- Acute maxillary sinusitis
- Community-acquired pneumonia
- Pharyngitis or tonsillitis
- Uncomplicated skin and skin structure infections
- Acute otitis media in pediatric patients
- Treatment and prophylaxis of disseminated mycobacterial infections
- Helicobacter pylori infection and duodenal ulcer disease in adults
Pharmacology
- Inhibition of microsomal protein synthesis in susceptible organisms
- Binding to the donor site on the 50S subunit of the bacterial ribosome
- Activity against most Gram-positive bacteria, Chlamydia, some Gram-negative bacteria, and Mycoplasmas
- Twice the activity of Erythromycin against H. influenzae
Dosage & Administration
- Dosage for acute bacterial exacerbation of chronic bronchitis in adults
- Dosage for acute maxillary sinusitis in adults
- Dosage for community-acquired pneumonia in adults
- Dosage for pharyngitis or tonsillitis in adults
- Dosage for uncomplicated skin and skin structure infections in adults
- Combination dosing regimens for H. pylori infection
- Dosage for acute otitis media in pediatric patients
Interaction
- Contraindications with HMG-CoA reductase inhibitors, gastroprokinetic agents, ergot alkaloids, antipsychotics, anti-gout agents, and antiarrhythmics drugs
Contraindications
- Contraindicated in patients with known hypersensitivity to clarithromycin, erythromycin, or any macrolide antibacterial drugs
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Abdominal pain
- Stomatitis
- Glossitis
- Headache
- Allergic reactions
- Taste perversion
- Transient central nervous system side effects
Pregnancy & Lactation
- Use in neonates and children in appropriate doses
- Caution advised for use during pregnancy and lactation
Precautions & Warnings
- Discontinue if severe acute hypersensitivity reactions occur
- Avoid in patients with known QT prolongation or receiving drugs known to prolong the QT interval
- Discontinue if signs and symptoms of hepatitis occur
- Increased risk of all-cause mortality in patients with coronary artery disease
Use in Special Populations
- Safety and effectiveness in pediatric patients 6 months and older
- Prevention of disseminated Mycobacterium avium complex (MAC) disease in pediatric patients 20 months and older with advanced HIV infection
Overdose Effects
- Ingestion of large amounts can produce gastrointestinal symptoms
- Altered mental status
- Paranoid behavior
- Hypokalemia
- Hypoxemia
Therapeutic Class
- Macrolides
Storage Conditions
- Store in a cool and dry place
- Protected from light & moisture
- Reconstituted suspension must be used within 7-14 days