A-Rox 50 mg/5 ml (Powder for Suspension)
Medicine Details
| Category | Details |
|---|---|
| Generic | Roxithromycin |
| Company | Ambee pharmaceuticals ltd |
| Also available as |
Product Title
- A-Rox
Categories
- Medicine
- Antibacterial
- Macrolide
- Therapeutic
Description
A macrolide with antibacterial properties similar to erythromycin. Effective against various infections caused by susceptible microorganisms.
Indications
- Treatment of respiratory infections like pneumonia, acute and chronic bronchitis
- Treatment of ENT infections like tonsillitis, pharyngitis, sinusitis, and otitis media
- Treatment of skin infections like folliculitis, furuncles, cellulitis, carbuncles, pyoderma, impetigo, and infected dermatitis
- Treatment of genital infections like urethritis, prostatitis, cervicitis, and salpingitis
Pharmacology
Inhibits protein synthesis by irreversibly binding to the 50s ribosomal subunits, thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting in stunted cell growth
Dosage & Administration
- Adult dose: 300 mg tablet once daily or 150 mg tablet twice a day for at least two days after resolution of symptoms
- Pediatric dose: 2.5 to 5 mg/kg body weight twice a day
Interaction
No affinity for cytochrome P-450 binding sites. Mild interaction with theophylline. No effect on the absorption by antacids, H2-receptor antagonists, and food
Contraindications
Not to be administered simultaneously with ergotamine or its derivatives
Side Effects
- Nausea
- Abdominal pain
- Diarrhoea
- Hypersensitivity rash
- Vomiting
- Dizziness
- Headache
- Pruritus
- Dyspepsia
- Flatulence
- Tinnitus
- Vertigo
- Constipation
Pregnancy & Lactation
Safety in pregnancy not established. Appears in breast milk in small amounts without adverse effects on the breastfed infant
Precautions & Warnings
Not to be used in patients with a history of hypersensitivity to the drug. Dose should not exceed 150 mg twice a day in patients with hepatic diseases
Therapeutic Class
- Macrolides