Pedilid 300 mg (Tablet)

Unit Price: ৳ 14.00 (3 x 10: ৳ 420.00)
Strip Price: ৳ 140.00

Medicine Details

Indications

  • Respiratory infections like pneumonia, acute and chronic bronchitis
  • ENT infections like tonsillitis, pharyngitis, sinusitis
  • Skin infections like folliculitis, furuncles, cellulitis
  • Genital infections like urethritis, prostatitis, cervicitis

Description

Macrolide with antibacterial properties similar to erythromycin.

Active Ingredients

Roxithromycin

Antibacterial Activity

  • Gram-positive bacteria
  • Gram-negative bacteria
  • Atypical pathogens like Mycoplasma and Chlamydia

Treatment Areas

  • Upper and lower respiratory tract infections
  • Otorhinolaryngological infections
  • Skin infections
  • Dental infections
  • Genital infections

Age Tolerance

Well tolerated by adults and children

Pharmacology

Inhibits protein synthesis by irreversibly binding to the 50s ribosomal subunits

Dosage & Administration

  • Usual Adult Dose: 300 mg tablet once daily or 150 mg tablet twice a day for at least 2 days
  • Usual Pediatric Dose: 2.5 to 5 mg/kg body weight twice a day

Absorption

Best administered on an empty stomach

Interaction

  • Cytochrome P-450 Affinity: None
  • Mild Interaction with: Theophylline
  • No Effect on:
    • Carbamazepine
    • Warfarin
    • Antacids
    • H2-receptor antagonists
    • Food

Contraindications

Simultaneous administration with ergotamine or its derivatives

Side Effects

  • Common Complaints:
    • Nausea
    • Abdominal pain
    • Diarrhoea
    • Hypersensitivity rash
  • Other Reported Effects:
    • Vomiting
    • Dizziness
    • Headache
    • Pruritus
    • Dyspepsia
    • Flatulence
    • Tinnitus
    • Vertigo
    • Constipation
  • Nature: Mostly minor and do not necessitate withdrawal of therapy

Pregnancy & Lactation Safety

  • Safety not established in pregnancy
  • Appears in breast milk in small amounts with no adverse effects in breastfed infants

Precautions & Warnings

  • Not to be used in patients with a history of hypersensitivity to the drug
  • In patients with hepatic diseases, the dose should not exceed 150 mg twice a day

Therapeutic Class

Macrolides

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