Roxcin 150 mg (Tablet)

Unit Price: ৳ 7.02 (2 x 10: ৳ 140.40)

Strip Price: ৳ 70.20

Medicine Details

Category	Details
Generic	Roxithromycin
Company	Alco pharma ltd
Also available as	Roxcin 300 mg tablet Roxcin 50 mg suspension

Macrolide antibiotic with antibacterial properties similar to erythromycin
Active against Gram-positive and Gram-negative bacteria, atypical pathogens like Mycoplasma and Chlamydia
Well tolerated by adults and children

Treatment of respiratory infections like pneumonia, acute and chronic bronchitis, and bronchopneumonia
Treatment of ENT infections like tonsillitis, pharyngitis, sinusitis and otitis media
Treatment of skin infections like folliculitis, furuncles, cellulitis, carbuncles, pyoderma, impetigo, and infected dermatitis
Treatment of genital infections like urethritis, prostatitis, cervicitis, and salpingitis especially if produced by Chlamydia trachomatis

Inhibits protein synthesis by irreversibly binding to the 50s ribosomal subunits, thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting in stunted cell growth

Adult dose: 300 mg tablet once daily or 150 mg tablet twice a day for at least two days after resolution of symptoms
Pediatric dose: 2.5 to 5 mg/kg body weight twice a day, with specific guidelines based on weight
Normal course of therapy is between 5 and 10 days

No affinity for cytochrome P-450 binding sites, unlikely to produce drug interaction mediated by this enzymatic system
Mild interaction with theophylline, though clinically relevant effects are not produced
No alteration in the pharmacokinetics of carbamazepine or warfarin
Antacids, H2-receptor antagonists, and food have no effect on the absorption of Roxcin

Should not be administered simultaneously with ergotamine or its derivatives, as it may provoke arterial spasm and severe ischemia

Well tolerated by patients of all age groups
Less than 4% of treated patients complain of side effects mainly nausea, abdominal pain, diarrhea, and hypersensitivity rash
Other reported side effects include vomiting, dizziness, headache, pruritus, dyspepsia, flatulence, tinnitus, vertigo, and constipation

Safety in pregnancy not established
Appears in breast milk in small amounts and does not produce adverse effects in the breastfed infant

Should not be used in patients with a history of hypersensitivity to the drug
In patients with hepatic diseases, the dose should not exceed 150 mg twice a day